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Path 18

Inflammatory Skin Disease

The cells that make up the epidermis are known as? keratinocytes
what do langerhans cells do process antigens
What do Merkel cells do? act as mechanoreceptors
Dermatitis is often used to refer to ? spongiotic dermatitis (also referred to clinically as eczema)
What is Acne Vulgaris a disease of the follicle in where there is occlusion by keratin and sebum resulting in the overgrowth of propionibacterium acnes
What are the open and closed comedones called blackheads and whiteheads
What is another term for vasculitis leukocytoclastic vasculitis
What is the hallmark of vasculitis palpable purpura
What are the pathological findings of vasculitis infiltration of the vessel walls by neutrophils, endothelial swelling, fragmentation of neuclei of neutrophils (leukocytoclasis), erythrocyte extravasation, and sometimes thrombotic vessel occlusion, and fibrin depositition
What is Erythema Multiforme eruption of macules, papules, vesicles, or bullae with a widespread distribution pattern
What is the name of erythema multiforme with mucous membrane involvement Stevens Johnson Syndrome
What is the name of the Erythema Multiforme in which there can be extensive exfoliation of the skin TEN toxic epidermal necrolysis
What are some triggering factors of Erythema Multiforme herpes simplex, other infectious agents, and drugs
What are the three main microscopic findings of EM vacuolar degeneration of the basilar layers, formation of eosinophilis, apoptotic bodies at the dermal-epidermal junction and at all levels of the epidermis
What is impetigo a superficial bacterial infection caused by S. Aureus or S. pyrogenes
How do patients with impetigo present? with erythematous papules that evolve into blisters or putules. These then rupture and produce the characteristic honey colored crusts
What is an example of a possible complication of impetigo poststreptococcal glomerulonephritis
Where are there aggregates of neutrophils with impetigo at the epidermal surface
Syphilis is a sexually transmitted disease caused by ? Treponema pallidum
What is the name of the primary lesion in syphilis chancre
Is the primary lesion of syphilis painful or painless? painless
What are the skin lesions of secondary syphilis condyloma lata, maculopapular eruptions that typically involve the palms and soles
What is the characteristic nodular or ulcerative lesion of the tertiary stage of syphilis Gumma
What is the inflammatory cell found commonly at all stages of syphilis plasma cells
Warts, or verrucae are cutaneous tumors induced by? types of HPV
What are the four main kinds of warts? Verruca Vulgaris, Vurruca Plantaris, Verruca plana, Condyloma acuminatum
What is the name of keratinocytes with pyknotic nuclei surrounding clear halos that may be aggregated near the epidermal surface? Koilocytes
What are flesh colored dome shaped papules or small nodules with central keratotic cores Molluscum Contagiosum
The causative agent in molluscum contagiosum is a member of what virus family poxvirus
What are the most common herpesvirus infections due to? herpes simplex 1 and 2, and varicella zoster virus
What are the most common superficial fungal infections caused by? Dermatophytes, Candida albicans, adn the yeast pityrosporum
What is the hyphal form of pityrosporum Malassezia furfur
What fungus is often a factor in diaper dermatitis Candida
What is the cause of tinea versicolor Malassezia furfur
What pathological changes do Dermatophytes and Candida infections often show changes of spongiotic dermatitis
Where is the most common location for scabies lesions fingerwebs, wrists, trunk, genitalia
Created by: UVAPATH1