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Blood System

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Answer
Functions of the Blood System   - to transport oxgygen, carbon dioxide, nutrients, electrolytes, vitamins, hormones, and wastes throughout the body - To protect the body with circulating white blood cells, antibodies of the immune system, and clotting factors  
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All cells come from   stem cells  
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An immature RBC   Reticulocyte. Becomes mature when enters bloodstream  
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Structure of Blood System   Blood is connective tissue -45% formed element -55% liiquid/plasma  
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Formed elements are comprised of   produced in the bone marrow - erythrocytes - carry oxygen - leukocytes - provide immunity - thrombocytes - key role in hemostasis (clotting)  
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Blood plasma consists of   -90% water -10% components transported throughout the body  
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Blood   fluid that circulates throughout the heart, arteries, capillaries, and veins, transporting oxygen and nutritive materials to the tissues  
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Blood : formed elements   blood cells  
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Blood : plasma   liquid portion of blood that carries formed elements, clotting factors, minerals, and proteins  
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Blood : serum   liquid portion of blood after removal of clotting factors and blood cells  
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Bone marrow (blood forming organ)   soft tissue within bone, with multiple functions including the production of blood cells  
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Bone marrow : erythropoietin (EPO)   hormone released by kidneys that stimulates red blood cell production in bone marrow  
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Bone marrow : hematopoiesis   formation of blood cells and other formed elements  
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Spleen (blood forming organ)   vascular lymphatic organ responsible for filtering blood, destroying old red blood cells, producing red blood cells before birth , and storing blood  
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Formed element : erythrocyte   blood cell that carries oxygen and carbon dioxide  
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Erythrocyte : Hemoglobin (HGB , Hb , Hgb)   protein in red blood cells that binds to oxygen; gives red blood cells the characteristic color  
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Iron (Fe)   essential trace element necessary for hemoglobin to transport oxygen on red blood cells  
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Erythrocyte : Macrocyte   a large red blood cell  
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Erythrocyte : Rh factor   protein substance present in the red blood cells of most people (85%) that is capable of inducing intense antigenic reactions  
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Formed element : leukocyte   white blood cell , largest blood cell , protects against pathogens, foreign substances, and cell debris  
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Leukocyte : granulocyte   white blood cell with visible granules; the three types of granulocytes are named according to the type of dye each is attracted to  
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Leukocyte : agranulocyte   white blood cell without clearly visible granules  
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Different types of leukocytes   -Granulocytes : neutrophil , eosinophil , basophil -Agranulocytes : lymphocyte , monocyte  
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Formed element : thrombocyte , platelet (PLT)   cell fragments in the blood that stick together, forming a clot  
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Blood Clotting : Clotting Factors   any of the various plasma components involved in the clotting process  
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Blood Clotting : Coagulation   clotting; changing from liquid to a solid state  
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Blood Clotting : Fibrin   elastic fiber protein needed in clotting and produced by fibrinogen  
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Blood Clotting : Fibrinogen   plasma protein that is converted into solid threads called fibrin  
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chrom/o , chromat/o   color  
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cyt/o   cell  
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erythr/o   red  
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granul/o   granules  
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hem/o , hemat/o   blood  
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immun/o   immune, safe  
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leuk/o   white  
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lymph/o   lymph  
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neutr/o   neutral  
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nucle/o   nucleus  
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path/o   disease  
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phag/o   eat, swallow  
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phleb/o   vein  
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plas/o   formation , growth  
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thromb/o   blood clot  
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auto-   self, same  
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basi- , baso-   base  
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macro-   large, long  
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micro-   small  
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mono-   one  
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pro-   before, promoting  
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poly-   many, much  
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-cyte   cell  
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-emia   blood (condition of)  
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-sis   condition, process  
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-gen   origin, production  
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-lysis   destruction , breakdown , separation  
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-osis   abnormal condition  
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-penia   deficiency  
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-philia   attraction for  
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-poiesis   production , formation  
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-rrhage   flowing forth  
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-y   condition of  
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hematopoietic   pertaining to the formation of blood cells  
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hemolytic   pertaining to the rupture or destruction of red blood cells  
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hemorrhagic   pertaining to profuse or excessive bleeding  
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hemostasis   stoppage or arrest of bleeding  
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anemia   condition in which the number of red blood cells, hemoglobin, or volume of packed cells is lower than normal  
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clotting disorder   condition characterized by an inability of blood to coagulate  
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hemochromatosis   excessive absorption and storage of dietary iron in body tissues causing dysfunction  
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pancytopenia   deficiency in all types of blood cells  
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polycythemia   increase of red blood cells  
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septicemia   spread of microorganisms or toxins through circulating blood  
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aplastic anemia   disorder in which bone marrow does not produce enough red blood cells to transport oxygen due to a lack of iron  
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pernicious anemia   disorder in which the number of red blood cells declines with simultaneous enlargment of individual cells (ex. macrocytes) due to an inability to absorb vitamin B-12  
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hemorrhagic anemia   blood loss anemia- disorder involving lack of red blood cells due to profuse blood loss  
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thalassemia   disorder caused by a genetic defect resulting in low hemoglobin production  
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sickle cell anemia   disorder caused by a genetic defect resulting in abnormal hemoglobin causing sickle-shaped red blood cells, which have difficulty moving through small capillary vessels  
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Normal platelet count   140,000 - 400,000  
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Increased bleeding time   <100,000  
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Spontaneous bleeding   <10,000  
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Hemophilia   bleeding disorder due to a deficiency of a clotting factor  
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thrombocytopenia   disorder involving low levels of platelets in blood  
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idiopathic thrombocytopenic purpura (ITP)   disorder marked by platelet destruction by macrophages resulting in bruising and bleeding from mucous membranes  
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von Willebrand disease   bleeding disorder characterized by a tendency to bleed primarily from the mucous membranes due to a deficiency of a clotting factor  
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albumin   measurement of this protein level; used to diagnose liver or kidney problems, inflammation, malnutrition, or dehydration  
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bilirubin   screen for liver disorders or anemia  
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blood smear   evaluation of the appearance and number of blood cells and the different types of white blood cells  
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complete blood count (CBC) , hemogram   automated count of all blood cells  
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CBC: erythrocyte sedimentation rate (ESR)   time measurement of red blood cells settling in a test tube over 1 hour; used to diagnose inflammation and anemia  
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CBC: hematocrit (HCT, hct)   volume of blood occupied by red blood cells; used to diagnose various disorders including anemia  
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CBC: hemoglobin (HGB, hgb, Hb) test   test for the red blood cell protein responsible for binding oxygen; used to diagnose various disorders including anemia  
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CBC: platelet count (PLT)   number of platelets present; used to diagnose bleeding disorders or bone marrow disease  
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CBC: red blood cell count   number of erythrocytes present; used to diagnose various disorders including anemia  
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CBC: white blood cell count   number of leukocytes present; used to diagnose various disorders, including infections and diseases, and for monitoring treatment  
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cross-matching   blood typing test for compatibility between donor and recipient blood  
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prothrombin time (PT)   measurement of time for blood to clot  
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WBC differential count, differential count   evaluation of the total percentage of leukocytes  
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phlebotomy, venipuncture, venotomy   incision into a vein to inject a solution or withdraw blood  
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blood transfusion (BT)   transfer of blood between compatible donor and recipient  
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apheresis   removal and replacement of a patient's own blood or donor blood after specific components have been removed  
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autologous blood   blood donated for future use by same patient; usually presurgical  
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homologous blood   blood donate from same species for use by a compatible recipient  
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blood component therapy   transfusion of specific blood components such as packed red blood cells, plasma, or platelets  
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plasmapheresis   removal and replacement of a patient's own blood after plasma has been removed and replaced with a plasma substitute  
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bone marrow aspiration (BMA)   removal of a small amount of fluid and cells from inside the bone with a needle and syringe  
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bone marrow transplant (BMT)   transfer of bone marrow from one person to another  
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rheumatology   medical specialty concerned with diagnosis and treatment of rheumatic conditions and autoimmune diseases  
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rheumatologist   a physician who specializes in rheumatology  
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allergology   medical specialty concerned with diagnosis and treatment of allergy and sensitivity  
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allergist   physician who specializes in allergology  
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hematology   medical specialty concerned with diagnosis and treatment of disorders of the blood and blood-forming organs  
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hematologist   physician who specializes in hematology  
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