| Question | Answer |
| No increase in red cell mass, but a decrease in plasma volume | Relative Erythrocytosis |
| Increase in red blood cell mass | Absolute Erythrocytosis |
| Significant decrease in total body RBC mass | Anemia |
| 5 parts of the CBC | Erythrocyte Count
Hematocrit
Hemoglobin Concentration
RBC Indicies
Peripheral Smear Review |
| Normal hematocrit | 45% or .45 |
| Mean Corpuscular Volume
80-100 fL | Normal |
| Mean Corpuscular Volume
< 80 fL | Microcytic |
| Mean Corpuscular Volume
> 100 fL | Macrocytic |
| Red cell diameter >8um
MCV >100
Oval or Round
Normochromic; no polychromasia | Macrocytosis |
| RBC diameter <6 um
MCV <80 fL
Hypochromic | Microcytosis |
| Red Cell Distribution Width represents... | Variation of red cell volume |
| Anisocytosis | Variation in cell Size |
| High RDW | Increase in heterogeneity of RBC size |
| Low RDW | More uniform RBC population |
| 5 Normochromic, normocytic anemias | Anemia of Chronic disease
Immune hemolytic disease
Anemia of acute hemorrhage
Aplastic anemia
End organ failure |
| 3 Hypochromic, microcytic anemias | Iron deficiency anemia
Thalassemia
Long standing anemia of chronic disease |
| 3 Macrocytic, normochromic anemias | Vitamin B12/Folate deficiency
Refractory anemiaa / Myelodysplastic Syndrome (MDS)
Liver disease |
| Immature red cells | Reticulocytes |
| Reticulocytes often have ____ coloration | Blue
From RNA |
| Formula for Corrected Reticulocyte Count | % observed Reticulosytes X Pt HCT
_________________________________
45 |
