| Question | Answer |
| Immunology | |
| Immunity | |
| Innate Resistance | |
| Monocytes / Macrophages | |
| Granulocytes | |
| Neutrophils. | |
| Eosinophils | |
| Natural Killer Cells | |
| Chemotaxins | |
| Opsonin | |
| Defensins | |
| Oxidative Burst | |
| Probiotics | |
| Prebiotics | |
| Granulocytic Phagocytes | |
| Zymogens | |
| Differentiate
First (barrier or external), second, and third (adaptive or acquired) lines of defense against infectious disease. | |
| Differentiate
Inducible vs noninducible defense mechanisms | |
| Discuss
characteristics of an immune response (specificity, memory, recognition) | |
| Discuss
mechanisms involved in the first line of defense | |
| Discuss
benefits vs disadvantages of iron supplements in terms of host defenses | |
| Discuss
hygiene hypothesis and its role in immune response | |
| Discuss
molecules involved in the attachment of PMNs to endothelial cells | |
| Discuss
suspected relations between CRP and heart disease | |
| Discuss
complement activation | |
| Discuss
the effects of complement act INSERT | |
| Discuss
the complement regulatory mechanisms | |
| Discuss
clinical features that ELEVATE complement protein concentrations | |
| Discuss
clinical features that DECREASE complement protein concentrations | |
| Compare
four types of acquired immunity (eg active natural immunity) | |
| Compare
roles physiologic factors have on host defense | |
| Compare
classical, alternative, and lectin pathways of complement activation, including mode of activation, proteins involved, etc. | |
| Contrast
cellular and humoral components of the innate immune responses | |
| Evaluate
role of defensins in host protection against infectious diseases | |
| Evaluate the roles of macrophages and neutrophils in inflammation and phagocytosis | |
| Evaluate the complement system in protection again infectious diseases | |
| Describe the role of toll-like receptors in innate immunity | |
| Describe the role of normal microbiota in protection against infection | |
| Describe the sites and cells in the mononuclear phagocytic system | |
| Describe granulocytic phagocytes | |
| List examples of mononuclear cells | |
| Describe how phagocytes kill bacteria, including the role of the oxidaivete burst | |
| Arrange the events of phagocytosis in order from activation of cells to killing of bacteria | |
| List examples of opsonins | |
| Describe the key features of the inflammatory response | |
| List proteins that are referred to as acute phase reactants | |
| Explain the principle of the c-reactive protein (CRP) test and cite advantages over the erythrocyte sedimentation rate (ESR) as an indicator of inflammation | |
| Explain the use of CRP for monitoring the course of a disease | |
| Explain why the activation of complement INSERT STUFF | |
| Describe C3 convertase and C5 convertase in both the classical and alternative complement pathways. | |
| Identify the two major amplification steps in the classical complement cascade | |
| Identify the complement components in the membrane attack complex (MAC) | |
| Describe how the MAC causes lysis of target cells | |
