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Random pharm Unit 1
Pharm II - Spring 2012
Question | Answer |
---|---|
Which non-opioids do not have anti-platelet effects? | Celecoxib (selective cox-2 inhib) and NAS (Salsalate, trisalicylate) |
NSAID with highest CV risk? | Celecoxib |
NSAID w/lowest CV risk? | Naproxen |
Opioid agonists have max biologic response when binding to which receptor? | Mu |
WHat are agents called that are related to morphine? | Phenanthrenes |
Which opioid should you take extreme caution with when switching to another? | Methadone!! |
What are good for bone pain? | NSAIDS |
WHat is inflammed, proliferating synovium called? | Pannus |
What should a pt taking steroids for RA make sure to get each day? | 1500 mg ca2+ and 400-800 IU of vit D/day |
WHat is the half life of leflunomide and why? | 14-16 days, undergoes enterohepatic recirculation |
How to get rapid clearance of Leflunomide? | Cholestyramine (bc binds to it) |
WHat is important to monitor with hydroxychloroquine? | Retinal toxicity -- periodic ophthalmic exams |
What should you tell patients about Sulfasalazine? | May notice yellow/orange-ing of skin/urine |