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Turnicky 02 Hypo/Mic
Trunichy: Hypochromic Microcytic Anemia
| Question | Answer |
|---|---|
| Deficiency in __ or ___ | Heme or globin chain synthesis |
| Result of deficiency in heme synthesis | Iron deficiency |
| Result of deficiency in globin synthesis | Thalassemia |
| Major storage form of iron | Ferritin |
| Ferritin synthesis is directly proportional to... | Total iron stores |
| Long term storage form of iron | Hemosiderin |
| What stain is used to see hemosiderin? | Prussian blue |
| Serum iron binding protein | Transferrin |
| Serum iron measures... | Transferrin bound iron |
| Use TIBC to discriminate between ___ and ___ | IDA and ACD |
| Normal transferrin saturation | 30% |
| Pt presents with: Decreased serum ferritin Decreased serum iron Increased TIBC Decreased %saturation What's the Dx? | Iron deficiency anemia |
| Two substances that can cause Acquired Sideroblastic Anemia | Alcohol and Lead |
| Inhibitory cytokines that adversely impact erythropoiesis | TNF-B IL-1/6 INF-gamma Hepcidin |
| One of the most common human diseases | IDA |
| Soluble iron storage form | Ferritin |