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Pathology-9
Breast
| Question | Answer |
|---|---|
| What is the main difference histologically between male and female breasts? | male breasts lack lobules |
| Where do most carcinomas of the breast arise? | ductal system (95% |
| What are the categories of diseases in the breast? | Developmental, Inflammation, Proliferative vs Non-Proliferative, Tumors |
| Which is more common? Proliferative or Non-Proliferative? | Non-Proliferative Fibrocystic disease |
| What is the histology of Non-Proliferative breast disease? | CASE of FIBROSIS: (C) Cystic dilation (A) apocrine metaplasia (S) Sclerosing adenosis (E) Epithelial hyperplasia & BLUE DOME CYSTS |
| BLUE DOME CYSTS | Non-proliferative fibrocystic disease |
| What are some of the causes of non-proliferative fibrocystic disease? | hormonal imbalance, fibrosis reactive to rupture |
| You have a pt with known fibrocystic disease. She scared. What do you tell her? | Fibrocystic disease is non-proliferative. It's the most common type of breast disease and there's NO RISK OF CARCINOMA. It's BENIGN. |
| You histologically see a biopsy with apocrine metaplasia, dilated ducts, some epithelial hyperplasia and some sclerosis. What is the guess? | fibrocystic disease |
| What are the types of proliferating breast disease? | PROLIFERATING PECS: (P) Papilloma (E) Epithelial Hyperplasia (may be atipical), (C) comlex lesions--radial scar (S) Sclerosing adenosis |