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What is the main difference histologically between male and female breasts? male breasts lack lobules
Where do most carcinomas of the breast arise? ductal system (95%
What are the categories of diseases in the breast? Developmental, Inflammation, Proliferative vs Non-Proliferative, Tumors
Which is more common? Proliferative or Non-Proliferative? Non-Proliferative Fibrocystic disease
What is the histology of Non-Proliferative breast disease? CASE of FIBROSIS: (C) Cystic dilation (A) apocrine metaplasia (S) Sclerosing adenosis (E) Epithelial hyperplasia & BLUE DOME CYSTS
BLUE DOME CYSTS Non-proliferative fibrocystic disease
What are some of the causes of non-proliferative fibrocystic disease? hormonal imbalance, fibrosis reactive to rupture
You have a pt with known fibrocystic disease. She scared. What do you tell her? Fibrocystic disease is non-proliferative. It's the most common type of breast disease and there's NO RISK OF CARCINOMA. It's BENIGN.
You histologically see a biopsy with apocrine metaplasia, dilated ducts, some epithelial hyperplasia and some sclerosis. What is the guess? fibrocystic disease
What are the types of proliferating breast disease? PROLIFERATING PECS: (P) Papilloma (E) Epithelial Hyperplasia (may be atipical), (C) comlex lesions--radial scar (S) Sclerosing adenosis
Created by: HSF2