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Nat. Review chpt.23a
Phases of inflammation
| Phase | Duration | Events |
|---|---|---|
| Initial | 24-48 hrs. after initiation | Vasodilation, edema, some leukocytes attracted to area, inflammatory chemicals released |
| Migratory | Days 2-5 | Start to see capillary budding into dammaged tissue, epithelialization of skin, chemotaxis, inflammatory barrior established, debridment or abscess formation |
| Proliferative | Days 5-21 | Fibroblasts form scar tissue where normal tissue has been destroyed, cells grow in random directions and adhere to all adjacent tissues |
| Remodeling | Over 21 days | Scar tissue reshaped and remodeled according to stresses on tissue, cell pattern is unidirectional, scar tissue cells are broken down and reabsorbed |