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2010 Pharm Drugs

SLCC Pharmacology Drugs

Use: Isoflurane (Forane) Inhalation anesthetic
Use: Lidocane (Xylocaine) 1) Infiltration, ophthalmic, dental, obstetric anesthesia. 2) Regional blocks 3) Nerve blocks NOTE: Local
Contraindication: Isoflurane (Forane) 1) Hypersensitivity 2) Predisposition to malignat hyperthermia NOTE: (can cause malignat hyperthermia)
Contraindication: Lidocane (Xylocaine) 1) Hypersensitivity ( Amide anesthetics, Sulfites, Methyl paraben) 2) Infection or inflamation at site of administration)
Adverse Effects: Isoflurane (Forane) Serious: Respiratory depression Common: Hypotension, Hypothermia, N/V
Adverse Effects: Lidocane (Xylocaine) Serious: Allergic reactions Common: Minimal unless accidental IV or intrathecal
Nursing Interventions: Isoflurane (Forane) • Low stimulus environment • Preoperative teaching Anesthesia Surgical procedure • Monitor respiratory status
Nursing Interventions: Lidocane (Xylocaine) • Calm reassurance • Read labels carefully • Right preparation for right procedure • Safety due to lack of sensation
Pharmacokinetics: lorazepam (Ativan) Highly lipid soluble and protein bound
Use: lorazepam (Ativan) • Management of anxiety • Short-term relief of anxiety symptoms
Contraindications: lorazepam (Ativan) • Hypersensitivity • Psychosis, hepatic disease • Acute narrow-angle glaucoma • <6 months of age
Adverse Effects: lorazepam (Ativan) Common: (Sedation and ataxia, Hangover effect) Serious (Anterograde amnesia, Psychosis & Suicidal tendencies)
Lifespan Alert: lorazepam (Ativan) • Elderly: reduce dose, start with smallest dose • Children: start with smallest dose • Cultural: Asians more sensitive
Nursing Interventions: lorazepam (Ativan) • Admin with food or water • Protect IM/IV from light • Divide oral doses (largest at bedtime) • Safety measures (effective contraceptive methods, limit use to 2 weeks, identification, impaired mental or physical ability) • Avoid other CNS depressants
SPASMOLYTICS: CENTRALLY and PERIPHERALLY acting Central: Baclofen (Liorsal) Peripheral: Dantrolene (Dantrium)
Pharmacodynamics: cyclobenzaprine (Flexeril) • Reduces pain and tenderness • Improves mobility
Use: cyclobenzaprine (Flexeril) Muscle spasms
Adverse Side Effects: cyclobenzaprine (Flexeril) Common: Sedation Serious: Agitation, auditory or visual hallucinations, seizures, psychotic symptoms NOTE: Effects with abrupt withdrawal
Lifespan Alert: cyclobenzaprine (Flexeril) • Elderly: more prone to sedation & anticholinergic effects
Nursing Interventions: cyclobenzaprine (Flexeril) • May take 1-2 days for optimal effects • Take exactly as prescribed • Avoid other CNS depressants • Never abruptly withdraw (with long term and high dose therapy)
Pharmacodynamics: baclofen (Lioresal) Reduces excessive reflex activity
Pharmacokinetics: baclofen (Lioresal) Crosses BBB
Use: baclofen (Lioresal) Muscle spasms or spasticity
Contraindications: baclofen (Lioresal) Patients that use spasticity to maintain posture or balance
Adverse Effects: baclofen (Lioresal) Common: Seditaion Serious: Agitation, auditory or visual hallucinations, seizures, psychotic symptoms NOTE: Effects with abrupt withdrawal
Lifespan Alert: baclofen (Lioresal) Elderly: more prone to sedation and other CNS effects
Nursing Interventions: baclofen (Lioresal) • Evenly space • Change positions slowly • Never abruptly stop • Avoid other CNS depressants • Diabetes: increases blood and urine glucose levels (use capillary blood for monitoring)
Pharmacodynamics: dantrolene (Dantrium) Direct effect on muscle cells (no CNS effects)
Pharmacokinetics: dantrolene (Dantrium) Metabolized to active metabolites
Use: dantrolene (Dantrium) • Muscle spasms or spasticity • Drug of choice for malignant hyperthermia
Contraindications: dantrolene (Dantrium) • Patients that use spasticity to maintain posture or balance • Active liver disorders
Adverse Effects: dantrolene (Dantrium) Common: Muscle weakness Serious: Fatal hepatitis (especially women >35 and taking estrogens)
Nursing Interventions: dantrolene (Dantrium) • Upper motor neuron disorders: may take 1 week or longer for therapeutic effects • Give with food or milk • Assist with ambulation • Teach symptoms of hepatitis
Drugs that Decrease Sodium Influx phenytoin (Dilantin)
Drugs that Decrease Calcium Influx ethosuximide (Zarontin)
Pharmacokinetics: phenytoin (Dilantin) • Absorption: rate & extent vary; IM-slow & unpredictable • 87-93% protein bound • CYP inducer Half-life increases with dosages Note: 10-20 Mcg/ml
Pharmacokinetics: ethosuximide (Zarontin) • Half-life o Children: 30 hours Adults: 60 hours
Use: phenytoin (Dilantin) Drug of choice for most seizure types (not absence)
Use: ethosuximide (Zarontin) Drug of choice for absence seizures
Contraindications: phenytoin (Dilantin) AV heart block Sinus bradycardia
Contraindications: ethosuximide (Zarontin) Hypersensitivity
Adverse Effects: phenytoin (Dilantin) Common: Sedation, nystagmus, ataxia, HA, nausea, gingival hyperplasia Serious: Blood dyscrasias, Lupus erythematosus Stevens-Johnson syndrome
Adverse Effects: ethosuximide (Zarontin) Common: Sedation, nausea, ataxia, HA, blurred vision, pruritis Serious: Pancytopenia
Nursing Interventions: phenytoin (Dilantin) • Maintain therapeutic concentration (10-20 mcg/mL) • Good oral hygiene • Frequent dental follow-up • Take with food (except milk & antacids) Abrupt withdrawal may cause status epilepticus
Nursing Interventions: ethosuximide (Zarontin) •Maint therapeutic concentration (40-100 mcg/mL) •Store drug in tight, lightresistant container, room temp •Mont CBC •Report S/S blood dyscrasias •May color urine pink, brown, or reddish-brown Abrupt withdrawal may cause status epilepticus (Rotten p
NARCOTIC ANALGESICS (Strong, Mild, Agonist\Antagonist) Strong: Morphine (Roxanol) Mild: Codeine Agonist\Antagonist: Pentazocine (Talwin)
Use: Morphine Moderate to severe pain
Contraindications: Morphine • Significant respiratory depression • Increased ICP • CNS depression
Adverse Effects: Morphine Common: Light-headedness, Dizziness, N/V Serious: Respiratory depression
Lifespan Alert: Morphine Avoid in premature infants or during labor of premature infants
Nursing Interventions: Morphine • Asses pain before & during therapy • Individualize dose • Monitor VS • Have naloxone readily available
Use: codeine • Mild to moderate pain • Cough suppressant
Contraindication: codeine • Respiratory depression • Other CNS depressant use
Adverse Effects: codeine common: Cough suppressant •Drowsiness, sedation, dry mouth, N/V, constipation •Analgesic Similar to morphine (milder) •N/V •Dizziness •Light-headedness •Euphoria serious: Respiratory depression
Lifespan Alert: Codeine Avoid in premature infants or during labor of premature infants Note: Same as morphone
Nursing Interventions: Codeine Same as morphine and avoid if patient’s health status requires a strong cough
Pharmcokinetics: pentazocine (Talwin) • Significant first-pass phenomenon • Bioavailability 20%
Use: pentazocine (Talwin) • Moderate to severe pain • Abused on the street
Adverse Effects: pentazocine (Talwin) Common: N/V, Dizziness, Light-headedness, Euphoria Serious: Respiratory & circulatory depression
Nursing Interventions: pentazocine (Talwin) Same as other narcotics and avoid alcohol and other CNS depressants
Use: dextroamphetamine • Narcolepsy • ADHD
Adverse Effects: dextroamphetamine Restlessness, insomnia, dizziness, overstimulation, palpitations, tachycardia, hypertension, dry mouth, unpleasant taste, diarrhea
Nursing Interventions: dextroamphetamine • Take with food in morning • Take at least 6 hours before bedtime • Baseline assessment to compare treatment outcomes • Avoid other stimulants • Abuse potential • Adhere to dosing scheduling
Pharmacokinetics: caffeine • Crosses BBB and placenta • Limited metabolism in neonates
Use: caffeine • Post-surgical respiratory depression • Neonatal apnea
Adverse Effects: caffeine • Caffeine withdrawal syndrome with abrupt cessation
Phamacodynamics: epinephrine Stimulates CV, skin & viscera, respiratory receptors NOTE: Open Glaucoma
Use: epinephrine • Anaphylactic shock • Cardiac emergencies • Asthma • Glaucoma
Contraindications: epinephrine • Hypersensitivity • Active labor • Closed angle glaucoma • General anesthesia • Severe organic cardiac disease • Shock other than anaphylaxis
Phamacodynamics: prazosin (Minipress) • Decreases sympathetic tone of vasculature • Dilate arterioles and veins • Lowers supine and standing BP
Use: prazosin (Minipress) • Refractory CHF • HTN • Raynaud vasospasm • Prostatic obstruction
Contraindications: prazosin (Minipress) Hypersensitivity Note: Orthostatic Hypotension
Pharmacodynamics: propranolol (Inderal) • Beta-1 blockade Heart & Kidneys (decrease BP) • Beta-2 blockade Many adverse effects (bronchospasm, hypoglycemia, peripheral vasoconstriction)
Phamacokinetics: propranolol (Inderal) First-pass phenomenon
Use: propranolol (Inderal) • Hypertension • Angina • Cardiac arrhythmias • Migraines
Contraindications: propranolol (Inderal) • Bradycardia • Complete heart block • Cardiogenic shock, uncompensated cardiac failure • Reactive airway diseases • Raynaud disease Note: Take pulse, don't stop abruptly, Rebound Tachycardia
Adverse Effects: epinephrine Common: • Fatigue • Sleep disturbances • Tremor • Weakness • Dizziness • Hyperglycemia • Tachycardia Serious: • Cardiovascular stimulation
Adverse Effects: prazosin (Minipress) Common: • Light-headedness • Dizziness • HA • Drowsiness • Weakness • Lethargy • Nausea • Palpitations Serious: • First dose syncope
Adverse Effects: propranolol (Inderal) Common: • Postural hypotension • Bronchospasm Serious: • MI
Nursing Interventions: epinephrine • Monitor CV status closely • Schedule doses to minimize sleep disruption • Allow appetite and meal times to coincide
Nursing Interventions: prazosin (Minipress) • No OTC drugs • Safety with CNS effects • Safe ways to deal with postural hypotension
Nursing Interventions: propranolol (Inderal) • Hypotensive stability may not occur for 2-3 weeks • Take exactly as prescribed • Never double the dose • Minimize stressors • Teach taking pulse • Safe mobility • Never abruptly stop taking
Pharmacodynamics: pilocarpine (Akarpine) • Topical: Miosis, decrease IOP • Oral: stimulates secretions of exocrine glands
Use: pilocarpine (Akarpine) • Simple and acute glaucoma • Pre & post-operative intraocular tension • Mydriasis • Xerostomia
Contraindications: pilocarpine (Akarpine) • Hypersensitivity • Oral: severe respiratory disease
Adverse Effects: pilocarpine (Akarpine) Common: • Blurred vision • Myopia Serious: • Cholinergic crisis • Bronchospasm
Nursing Interventions: pilocarpine (Akarpine) • Topical: administer into conjunctival cul-de-sac & use aseptic technique • Have antidote available • S/S of cholinergic crisis Note: More Secretions
Pharmacodynamics & Pharmacokinetics: nicotine • Pharmacodynamics: Potent ganglionic and CNS stimulant • Pharmacokinetics: Extensive first-pass phenomenon
Use: nicotine Adjunct to smoking cessation programs
Contraindications: nicotine • Immediately post MI • Life threatening dysrhythmias • Severe angina
Adverse Effects: nicotine Common: • Erythema • Pruritis & burning • HA • Insomnia Serious: • Vasculitis
Nursing Interventions: nicotine • Adhere to recommended dosing • Promote rest and sleep by adjusting timing of last dose • Avoid other CNS stimulants
Pharmacodynamics: atropine • Blocks GI & smooth muscle, exocrine glands, heart, eye
Use and Contraindications: atropine Use: • Prevent postoperative secretions • Drug of choice in cholinergic crisis Contraindications: • Hypersensitivity to sulfites • Myasthenia gravis • Acute MI
Adverse Effects: atropine Common: • Blurred vision • Constipation • Dry mouth • Urinary retention Serious: • Severe bradycardia
Nursing Interventions: atropine • Take exactly as prescribed • Good oral hygiene • Fluid replacement • Safety issues for blurred vision • Avoid OTC and herbal meds Note: Less Secretions
DRUGS FOR UPPER RESPIRATORY SYSTEM ANTITUSSIVE: dextromethorphan (Benylin) DECONGESTANT: psuedoephedrine ANTIHISTAMINE: fexofenadine (Allegra) EXPECTORANT: guaifenesin
Pharmacodynamics: dextromethorphan (Benylin) Suppresses cough reflex
Use & Contraindications: dextromethorphan (Benylin) Use: • Nonproductive cough Contraindications: • cough resulting from emphysema or asthma
Adverse Effects: dextromethorphan (Benylin) Common: • N/V and irritability Serious: • Drowsiness • Dizziness
Lifespan alert: dextromethorphan (Benylin) Not for children <6
Nursing Interventions: dextromethorphan (Benylin) • Administer at evenly spaced intervals • Safety precautions • Seek medical attention if cough not relieved
Pharmacodynamics: psuedoephedrine • Nasal vasoconstriction • Promotes sinus drainage
Use & Contraindications: psuedoephedrine Use: • Nasal congestion Contraindications: • Severe hypertension • Severe cardiac disorders
Adverse Effects: psuedoephedrine Common: • Tachycardia • Palpitations • Nervousness Serious: • Dysrhythmias • Hypertension • Coronary vasospasm
Nursing Interventions: psuedoephedrine • Increase fluid intake • Use humidifier • Safety precautions • Take as prescribed (not longer than 4 days)
Pharmacodynamics: fexofenadine (Allegra) • Blocks histamine • Anticholinergic effects • Antipruritic effects
Use & Contraindications: fexofenadine (Allegra) Use: • Allergic disorders Contraindications: • Children <12
Adverse Effects: fexofenadine (Allegra) Common: • Flu-like symptoms • N/V • Dysmenorrhea • Drowsiness Serious: • QT prolongation
Nursing Interventions: fexofenadine (Allegra) • Increase fluid intake • Use humidifier • Safety precutions • Use with allergic symptoms
Pharmacodynamics: guaifenesin • Increases output of respiratory fluids • Increases productive cough
Use & Contraindications: guaifenesin Use: • Dry, nonproductive cough Contraindications: • Hypersensitivity
Adverse Effects: guaifenesin • N/V • Anorexia
Nursing Interventions: guaifenesin • Good pulmonary toilet • Eat small frequent meals • Medical attention if cough not resolved
Pharmacodynamics: albuterol (Proventil) • Relaxes bronchial smooth muscle
Use and Contraindications: albuterol (Proventil) Use: • COPD • Asthma Contraindication: • Hypersensitivity
Adverse Effects: albuterol (Proventil) Common: • Throat irritation, • palpitations • tachycardia • anxiety • tremors • increase BP Serious: • Bronchospasm • urticaria • angioedema
Nursing Interventions: albuterol (Proventil) • Correct use of inhalation device • Do not overdose • Used first for all acute symptoms
Pharmacodynamics & Pharmacokinetics: flunisolide (AeroBid) Pharmacodynamics • decrease leukotrienes • decrease inflammatory cells • decrease mucus Pharmacokinetics: • Most effective Anti-inflam
Use and Contraindications: flunisolide (AeroBid) Use: • CAL & asthma Contraindication: • Caution: active infection of respiratory system
Adverse Effects: flunisolide (AeroBid) Common: • Dry mouth, dysphonia Serious: • Oral candidiasis, systemic absorption
Nursing Interventions: flunisolide (AeroBid) • Peak effect in 1-2 week • Take daily • Rinse mouth after each administration • Use spacer
Pharmacodynamics: cromolyn sodium (Intal) • Exact mechanism unclear
Use and Contraindications: cromolyn sodium (Intal) Use: • Prophylaxis of allergic symptoms Contraindications: • Hypersensitivity • Acute symptoms
Adverse Effects: cromolyn sodium (Intal) Common: • Dry throat, cough, wheezing Serious: • Bronchospasm, anaphylaxis
Nursing Interventions: cromolyn sodium (Intal) • Correct use of inhalation device • Take daily • May take weeks for improvement
Pharmacodynamics: zafirlukast (Accolate) • decrease bronchoconstriction • decrease mucous secretion • decrease vascular permeability
Use and Contraindications: zafirlukast (Accolate) Use: • Management of COPD and Asthma Contraindications: • Hypersensitivity to povidone, lactose, titanium dioxide, cellulose
Adverse Effects: zafirlukast (Accolate) Common: • HA, gastritis, pharyngitis, rhinitis Serious: • Hepatic failure, Churg-Strauss syndrome
Nursing Interventions: zafirlukast (Accolate) • Administer daily • Take as prescribed • Will not abort acute attack
Class & Drug: penicillin G Class: PENICILLINS Drug: penicillin G
Pharmacodynamics & Pharmacokinetics: penicillin G Pharmacodynamics: • Bacteriocidal Pharmacokinetic: • Unstable in gastric acid • Protein binding • Does not cross BBB
Use and Contraindications: penicillin G Use: • Gram-positive • Anaerobes • Spirochetes • Prophylactic bacterial endocarditis Contraindications: • Hyper-sensitivity o Penicillins o Cephalosporins o Imipenem
Adverse Effects: penicillin G Common: • N/V • Diarrhea Serious: • Hyper-sensitivity
Nursing Interventions: penicillin G • Give on empty stomach • C&S for gram-negative • Monitor I&O • Take as prescribed • Take entire prescription • S/S allergic reaction
Class & Drug: cefazolin (Ancef, Kefzol) Class: CEPHALO-SPORINS Drug: cefazolin(Ancef, Kefzol)
Pharmacodynamics & Pharmacokinetics: cefazolin (Ancef, Kefzol) Pharmacodynamics: • Bacteriocidal Pharmacokinetics: • Does not cross BBB
Use and Contraindications: cefazolin (Ancef, Kefzol) Use: • Gram-positive • Anaerobes • Spirochetes • GI/GU surgery Contraindications: • Hyper-sensitivity o Cephalo-sporins o Penicillins
Adverse Effects: cefazolin (Ancef, Kefzol) Common: • N/V • Diarrhea Serious: • Hyper-sensitivity
Nursing Interventions: cefazolin (Ancef, Kefzol) • C&S for gram-negative • IM: large muscle • Take as prescribed • S/S allergic reaction
Class & Drug: Ciprofloxacin (Cipro) Class: FLUORO-QUINOLONES Drug: Ciprofloxacin(Cipro)
Pharmacodynamics & Pharmacokinetics: Ciprofloxacin (Cipro) Pharmacodynamics: • Bacteriocidal Pharmacokinetic: • Minimal penetration to CSF
Use and Contraindications: Ciprofloxacin (Cipro) Use: • Aerobic gram-negative Contraindications: • Hyper-sensitivity • Children • Pregnancy • Breast-feeding
Adverse Effects: Ciprofloxacin (Cipro) Common: • GI Serious: • Arthropathy
Nursing Interventions: Ciprofloxacin (Cipro) • Complete full course • Small frequent meals
Class & Drug: Sulfamethoxazole-trimethoprim (SMZ-TMP, Bactrim) Class: SULFONAMIDES Drug: Sulfamethoxazole-trimethoprim (SMZ-TMP, Bactrim)
Pharmacodynamics & Pharmacokinetics: Sulfamethoxazole-trimethoprim (SMZ-TMP, Bactrim) Pharmacodynamics: • Bacteriostatic Pharmacokinetic: • Crosses BBB
Use and Contraindications: Sulfamethoxazole-trimethoprim (SMZ-TMP, Bactrim) Use: • UTI • Pneumocystitis carinii pneumonia • Legionella, shigella, salmonella • Haemophilus influenzae • Strep Contraindications: • Hypersensitivity • G6PD or other folate deficiency • Urinary obstruction • Term pregnancy • no <2 months
Adverse Effects: Sulfamethoxazole-trimethoprim (SMZ-TMP, Bactrim) Common: • N/V • Diarrhea Serious: • Hematopoietic effect • Crystalluria • Stevens-Johnson syndrome
Nursing Interventions: Sulfamethoxazole-trimethoprim (SMZ-TMP, Bactrim) • Give on empty stomach • Increase fluids • Strategies to avoid photosensitivity & crystalluria
ANALGESICS Common Adverse Effect Discolor urine
Class & Drug: acetylsalicylic acid (Aspirin, Bayer Aspirin) Class: NSAIDS Salicylates Drug: acetylsalicylic acid (Aspirin, Bayer Aspirin)
Pharmacodynamics & Pharmacokinetics: acetylsalicylic acid (Aspirin, Bayer Aspirin) Pharmacodynamics: • Antipyretic • Anti-inflammatory • Antithrombotic Pharmacokinetic: • Protein bound • Crosses placenta • Enters breast-milk
Use and Contraindications: acetylsalicylic acid (Aspirin, Bayer Aspirin) Use: • Analgesic • Antipyretic • Anti-inflammatory • Antiplatelet Contraindications: • Peptic ulcer disease • Gout • Renal or hepatic impairment • Bleeding disorders • Anticoagulation therapy
Adverse Effects: acetylsalicylic acid (Aspirin, Bayer Aspirin) Common: • GI Serious: • Hepatic & renal toxicity
Lifespan Alert: acetylsalicylic acid (Aspirin, Bayer Aspirin) • children: do not give with varicella or flu-like symptoms • do not give in pregnancy • monitor patients >60
Nursing Interventions: acetylsalicylic acid (Aspirin, Bayer Aspirin) • give with food or milk • inquire about OTC drugs • monitor S/S for GI distress or bleeding, anemia, hepatotoxicity, renal failure • keep in safe place
Class & Drug: ibuprofen Class: Prostaglandin synthetase inhibitors Drug: ibuprofen (Motrin, Advil)
Pharmacodynamics & Pharmacokinetics: ibuprofen Pharmacodynamics: • Inhibits prostaglandins Pharmacokinetic: • Highly protein bound • Slowed absorption with food
Use and Contraindications: ibuprofen Use: • Anti-inflammatory • Analgesic • Antipyretic Contraindications: • Active GI diseases
Adverse Effects: ibuprofen Common: • GI Serious: • Hepatic and renal toxicity
Lifespan Alert: ibuprofen • pregnancy: category D in 3rd trimester • monitor carefully patients >60
Nursing Interventions: ibuprofen • give with food or milk • inquire about OTC drugs • alcohol and cigarette smoking
Class & Drug: acetaminophen Class: Para-aminophenol derivatives Drug: acetaminophen
Pharmacodynamics & Pharmacokinetics: acetaminophen Pharmacodynamics: • Exact mechanism unknown • Weak inhibitor or COX
Use and Contraindications: acetaminophen Use: • Mild to moderate pain • Antipyretic (fever) Contraindications: • Hepatic disease • Viral hepatitis • Alcoholism (no with liver problems)
Adverse Effects: acetaminophen Common: • Rash • Urticaria • Nausea Serious: • Hepatic or renal toxicity
Lifespan Alert: acetaminophen • children: drug of choice for flu or flu-like symptoms • pregnancy & lactation: drug of choice
Class & Drug: Class: Disease-Modifying Antirhuematic Drugs Drug: Methotrexate (Rheumatrex)
Pharmacodynamics & Pharmacokinetics: Pharmacodynamics: • Immunosuppressive effects Pharmacokinetic: • Absorption decreased with food
Use and Contraindications: Use: • Rheumatoid arthritis Contraindications: • Immunosuppression • Blood dyscrasias • Pregnancy
Adverse Effects: Common: • Nausea • HA • Stomatitis, gingivitis • Alopecia Serious: • Bone marrow depression
Nursing Interventions: • Remain hydrated • Take vitamin B • Educate adverse effects and to report to provider • Monitor CBC, liver and renal function tests
Pharmacodynamics & Pharmacokinetics: hydrochlorothiazide (Hydrodiuril) Pharmacodynamics: • Weak diuretic effect • increase excretion of Na+, Cl-, K+, Mg, bicarbonate • decrease excretion of Ca+ • May decrease GFR & increase BUN Pharmacokinetics: • 50% bound to protein
Use and Contraindications: hydrochlorothiazide (Hydrodiuril) Use: • HTN • Edema with CHF, hepatic or renal disease, secondary drug use Contraindications: • Severe renal disease
Adverse Effects: hydrochlorothiazide (Hydrodiuril) Common: • Dizziness, light-headedness, vertigo, N/V Serious: • Aplastic anemia • Thrombocytopenia
Nursing Interventions: hydrochlorothiazide (Hydrodiuril) • Give in AM • Monitor BP, weight, I/O, serum electrolyte levels • Importance of blood work (electrolytes, CBC)
Created by: wfawcett