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WEEK 2:
Pharmaceutical factors affecting drug bioavailability + dose calculations:
| Question | Answer |
|---|---|
| types of oral preparations to treat GIT conditions (3) | suspension, tablet, and capsule |
| examples of fast oral formulations | aqueous, solutions, syrups, and elixirs |
| examples of middle pace oral formulations | suspensions, chewable tablets, granules, capsules, and conventional tablet |
| examples of slow oral formulations | compressed tablets, enteric coated tablets, and controlled release tablets |
| why should certain drugs not be prescribed as same formulation | their bioavailability may change |
| modified or sustained release preparations | formulated to resist dissolution and may be used to reduce absorption rate and prolong action, and deliver drug to specific region of GIT |
| morphine | |
| nifedipine | acts as a dihydropyridine (DHHP) calcium channel blockers (CCBs) used to treat hypertension and angina |
| nifedipine half life | |
| nifedipine features | |
| omeprazole | |
| therapeutic uses of omeprazole | |
| enteric coat meaning | acid resistance coat capsule |
| effect of omeprazole (26) | |
| when should IV omeprazole be given | |
| glyceryl trinitrate and fentanyl | |
| skin patches available (2) | |
| fentanyl patches | |
| patients who cannot swallow | |
| different types of insulin preparations | |
| depot injections (deep IM) | |
| unit | measure of power or action of drug (measure of biological activity) |
| factors affecting bioavailability | dosage form and brand (different brands have different bioavailabilities) |