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WEEK 1:

Plenary:

QuestionAnswer
symptom physical/ mental feature indicating a disease that patient complains of
sign indication of a disease detectable by medical practitioner even if patient not aware
symptoms of crohns disease diarrhoea (+/- presence of blood), abdominal pain, weight loss, intestinal obstruction due to strictures, fistulae (often perianal), abscesses, good and bad days, systemic systems eg anorexia
signs of crohns disease dehydration, anaemia, abdominal tenderness, weight loss, and during severe exacerbation/ sepsis - hypotension, tachycardia and pyrexia
what diagnostic test is used for patients with suspected severe IBD AXR for initial assessment
calprotectin small calcium binding protein
what to use when differentiating between IBD and IBS calprotectin
how does calprotectin work in a positive test concentration in faeces correlates well with severity of intestinal inflammation
normal faecal calprotectin predictive value for IBD very high negative
investigations that can be used endoscopy into ileum with biopsies, CT scan, MRI, ultrasound, and small bowel capsule
how are diagnosis confirmed clinical evaluation and endoscopic, histological radiological, and biochemical investigations
when would a patient with crohn's be admitted to hospital severe abdominal pain, severe diarrhoea (>8 times a day), patient is systemically unwell with a fever, evidence of bowel obstruction
treatment for crohns IV fluids, analgesia, steroids, close monitoring, if complications eg bowel obstruction then consider surgery
long term management for crohn's long term therapy as chronic disease
how is remission induced and maintained induced by steroids and maintained by immunomodulators
complications of crohn's strictures in bowel (leading to bowel obstruction), short bowel syndrome, malnutrition, osteoporosis, deficiencies (iron, B12, folate), and gallstones
therapeutic drug monitoring (TDM) as treatment for crohns increase use of infliximab levels, adalimumab levels, anti drug antibodies
importance in nutrition in crohn's iron deficiency management, vitamin B12 monitoring, vitamin D replacement, dietician involvement
example of malabsorptive condition short bowel syndrome
short bowel syndrome malabsorption disorder following removal of/ part of small bowel
Created by: 22tango
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