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WEEK 1:

Introduction to GI tract:

QuestionAnswer
upper GIT route mouth -> oesophagus -> stomach -> duodenum (small intestine)
lower GIT route small intestine -> large intestine (colon) -> anus
upper GI (bleed) above duodenojejunal junction
lower GI (bleed) below duodenojejunal junction
clinical definition of GIT from point of view of GI bleeding
diagnostic definition of GIT from point of view of endoscopic imaging + duodenojejunal junction
diagnostic upper GIT oesophagus, stomach, duodenum
diagnostic lower GIT jejunum, ileum -> colon, rectus, anus
conventional upper GIT mouth to ileum
conventional lower GIT caecum to anus
regions of stomach include (2) external and internal features
external stomach regions cardia, fundus, body, pyloric antrum, pyloric canal, and pylorus
fundus of stomach bulges upwards and is sometimes full of gas
body of stomach cardiac orifice to angular incisure
shape of pyloric antrum of stomach funnel shape
pylorus of stomach sphincter regions where TPP (trans pyloric plane) runs through
surfaces of stomach (2) anterior and posterior
openings of stomach (2) cardiac orifice and pyloric orifice
curvatures of stomach (2) lesser and greater curvature
internal features of stomach rugae
rugae can be seen using which diagnostic test radiograph
rugae longitudinal folds which are stretched when stomach becomes full and lining becomes flat
relations in stomach (anything lying around eg above or behind) (2) peritoneal and visceral relations
peritoneal folds gastrophrenic ligament, gastrosplenic ligament, lesser omentum, and great omentum
gastrophrenic ligament has 2 layers and attaches the fundus of the stomach to the diaphragm
gastrosplenic ligament has 2 layers and attaches the body of the stomach to the spleen
lesser omentum has 2 layers and attaches the lesser curvature of the stomach to the liver
greater omentum has 2 layers and attaches the greater curvature of the stomach to the liver
how does the greater omentum protect against infection (policeman of the abdomen) acts as a first line of defense by physically containing infections within the abdomen
where is the omental bursa (lesser sac) behind stomach, behind gastrosplenic ligament, behind greater stomach, in front of great vessels and vertebral column
where does the omental bursa (lesser sac) and greater sac communicate omental foramen
explain barium meal imaging in stomach radio-opaque barium ingested to see peristaltic contraction of small intestine via narrowing in radiograph
anterior visceral relations in stomach is made of (3) liver (left lobe), diaphragm and anterior abdominal wall
posterior visceral relations - structures in the stomach (6) pancreas, splenic artery, left kidney, left adrenal gland, mesocolon, and spleen
superior visceral relation of stomach oesophagus and left dome of diaphragm
main stomach blood supply coeliac trunk
coeliac trunk single midline trunk close to aortic hiatus (T12) and is the main artery supplying stomach
branches of celiac trunk include right gastric (branching off to hepatic artery), right gastroepiploic (gastro-omental) branches of gastroduodenal artery), left gastroepiploic (branch of splenic artery), and short gastric (branches of splenic artery)
venous drainage of stomach tributaries of portal vein
innervation/ nerve supply of stomach (2) parasympathetic and sympathetic
parasympathetic nerves in stomach (2) left and right vagus nerves
what do the left and right vagus nerves do in stomach give rise to anterior and posterior vagal trunks respectively
due to rotation of gut, what happens to left and right sides of stomach left vagus and side of stomach become anterior and right vagus and right side of stomach becomes posterior
anterior and posterior vagal trunks branch into anterior and posterior gastric nerves
anterior gastric nerves gives branch to pylorus and liver (through hepatoduodenal ligament)
sympathetic nerve supply in stomach arises from T6-T9 spinal cord segments and passes to coeliac plexus via greater splanchnic nerve and carries some pain transmitting fibres
referred pain definition aka reflective pain is pain perceived at a different location other than site of painful stimulus
referred pain in stomach Visceral referred pain Visceral sensory fibers join spinal T6 - T9 T6-T9 dermatome Epigastric region Poorly localized
lymphatic drainage in stomach coeliac lymph nodes around coeliac axis (T12) which drain to cisterna chyli-thoracic duct
where do lymphatic vessels and nodes follow arteries like left/right gastric arteries, splenic artery running in gastrosplenic and lienorenal ligaments, right gastroepiploic artery in greater omentum
where could gastric carcinoma spread through lymphatics
duodenum shortest part of small intestine and is mostly retroperitoneal
parts of duodenum (4) superior (intraperitoneal and retroperitoneal), descending, horizontal, and ascending
internal feature of first part of duodenum smooth mucosal lining
internal feature of last parts of duodenum mucosa with circular folds (plicae circulares)
bile duct and pancreatic duct empty into medial wall of descending duodenum
opening of duct in duodenum forms raised bump on mucosa aka major duodenal papilla
other internal features of duodenum sometimes accessory pancreatic duct and minor duodenal papilla
relationships of duodenum (3) superior part (L1), descending part (L2), horizontal part
superior part (L1) of duodenum includes liver, gallbladder, hepatoduodenal ligament, and gastroduodenal artery
descending part (L2) of duodenum includes head of pancreas, bile duct, and pancreatic duct
horizontal part (L3) of duodenum lies over aorta/IVC and under superior mesenteric vessels
blood supply of duodenum includes (2) superior pancreaticoduodenal artery (coeliac branch) and inferior pancreaticoduodenal artery (superior mesenteric artery)
superior pancreaticoduodenal artery supplies duodenum above major papilla
inferior pancreaticoduodenal artery supplies duodenum below major papilla
branches of superior mesenteric artery supplies midgut from second part of duodenum to the left colic flexure
venous drainage in duodenum via superior mesenteric vein which unites with splenic vein at the neck of the pancreas to form the hepatic portal vein
duodenum nerve supply vagus nerve (CN X) via parasympathetic innervation and celiac plexus via sympathetic innervation
duodenum lymphatic drainage (2) anterior and posterior drainage
anterior lymphatic drainage in duodenum drains into pancreaticoduodenal lymph nodes and pyloric lymph nodes which are located along the arteries
posterior lymphatic drainage in duodenum drains into the superior mesenteric lymph nodes and passes posterior to the head of the pancreas
jejunum features heavily folded (plicae circulares) and have a lot of villi
where are plicae circulares most developed in jejunum
describe the epithelium covering the villi in jejunum simple columnar epithelium with cells that have microvilli on luminal surface which faces lumen
ileum has plicae which become less and less obvious further down the small intestine and are absent in the lower part of the ileum. Villi also become shorter and less numerous. Lumen gradually narrows.
mesentery double fold of peritoneal tissue that suspends small intestine and large intestine from posterior abdominal wall
how to identify jejunum in operation by its location and by the arrangement of arteries in mesentery (arterial arcades are low with long terminal branches supplying intestine)
vasa recta straight branches coming off arterial arcades
how to differentiate between jejunum and ileum arrangement of arteries in mesentery - in the ileum the arterial arcades are heaped up and terminal arteries branches are short with a thinner wall than the jejunum. Ileum also has Peyer's Patches (lymphoid tissue) seen along the antimesenteric border.
ascending part of duodenum (L2) runs along inferior border of pancreas and runs up to join duodenojejunal flexure which is held up by the ligament of Treitz (muscle strap derived from diaphragm and duodenum)
inferior pancreaticoduodenal artery first branch of superior mesenteric artery which supplies the lower half of the duodenum
where do the jejunal and ileal arteries arise from left side of SMA
where do the middle colic, right colic, ileocolic and appendicular arteries arise from right side of SMA
describe the position of the branches suppling the large intestine all the branches supplying the large intestine anastomose with one another EXCEPT the appendicular (end artery)
parasympathetic nerve fibres innervating duodenum originate from anterior and posterior vagal trunks and pass through the celiac plexuses and synapse in the gut plexuses in the duodenum
sympathetic nerve fibres innervating duodenum originate from T5 through T9 spinal cord levels
obstruction is characterised by abdominal swelling, pain, vomiting, and constipation - and when untreated it can lead to dehydration and death
difference in terminal vessels and arterial arcades in jejunum and ileum jejunum has long terminal vessels and low arterial arcades whereas the ileum has short terminal vessels and high 'heaped up' arterial arcades
Created by: 22tango
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