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WEEK 22:

Lung cancer epidemiology:

QuestionAnswer
lung cancer incidence over time increase
social deprivation and smoking strong associated between lung cancer incidence and deprivation in both males and females (so the more deprived the higher the smoking prevalence)
how is social deprivation and LC measured (4) unemployment, non car ownership, non home ownership, and household overcrowding
risk factors for LC (5) tobacco, air pollution (outdoor and household- second hand smoking), environmental/ occupational exposures (radon or asbestos) , gender, race
particulate matter in outdoor pollution level 1 carcinogen by IARC
3 billion people cook using polluting open fires/ simple stoves eg (3) kerosene, biomass (wood, animal dung and crop waste), and coal
radon radioactive gas released from normal decay of elements eg uranium, thorium and radium in rocks and soil
types of asbestos (2) chrysotile and amphibole
compare males and females who smoke females who smoke show higher levels of polycyclic aromatic hydrocarbon DNA adducts due to possible synergistic interaction between oestrogens and tobacco compounds
most common cancers in males and females UK lung
male to female ratio of lung cancer annual incidence in the UK 11:10 (in 1975 was 39:10 it is DECREASED)
how many diagnoses of lung cancer per year UK 1000 extra diagnoses per year
median age for lung cancer 73
highest rates age for lung cancer 80-85
how has pathological subtypes (carcinoid, SCLC, and NSCLC) changed over time both SCLC and squamous reduced
all the factors influencing and associated with lung cancer (8) gender, age, family history, genetic factors, lifestyle, environmental, race, and ethnicity
Created by: kablooey
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