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WEEK 18:
Respiration Under Unusual Conditions:
| Question | Answer |
|---|---|
| phases of ventilation and exercise (3) | beginning, moderate, and strenuous |
| start of exercise | normal PaCO2 and PaO2 levels with increased ventilation controlled and detected by proprioceptors in the neural mechanism |
| moderate exercise | normal PaCO2 and PaO2 with ventilation to a plateau as CO2 has been released back to normal levels controlled by central chemoreceptors on the medulla which detect H+ changes |
| strenuous exercise | increased body temperature and increased H+ from acid produced (aerobic metabolism) causing increased ventilation/hyperventilation from 5-6l/min to 120l/min to decrease PaCO2 and H+ levels |
| how is skeletal muscle contraction a cardiovascular adaptation for exercise | compresses blood vessels to direct blood into heart and lungs to increase cardiac output to active muscles used in exercise |
| acute hypoxia detected by what | peripheral chemoreceptors |
| as ventilation increases at high altitudes what happens | PaCO2 falls and PO2 increases, and CSF becomes alkaline leading to higher levels of HCO3- which are exported by choroid plexus cells then through urine to correct pH |
| hours in altitude | breathing is controlled and hypoxia avoided by increasing ventilation |
| days in altitude | alkalinity of blood corrected by excretion of HCO3- in urine |
| adaptations to high altitudes (4) | increased ventilation, polycythaemia (make more RBC to carry more O2), increased urination, and increased cardiac output |
| adaptations to high altitudes are only effective up to where | 5500m |
| dangers of descent | LUQ (abdomen) pain due to enlargement of spleen as it breaks down excess RBCs |
| pressure and weight 10.1m diving | pressure exerted by weight from atmospheric pressure and pressure from weight of water |
| every 10.1m of depth is equal to how much atmospheric pressure | 1 |
| boyles law | pressure is inversely proportional to volume at constant pressure (smaller space = higher pressure) |
| pressure in descent | increased |
| pressure in ascent | decreased |
| nitrogen consequences when diving | increased pressure causes more N2 to dissolve in body leading to nitrogen narcosis (drowsiness, euphoria, weakness and unconsciousness) |
| nitrogen consequences when ascending | already dissolved N2 becomes N2 gas bubbles leading to decompression sickness (the bends) with excruciating pain and fatigue |
| consequences of space flight appearance | puffy face and bird legs (small legs) |
| acute consequences of space flight (3) | motion sickness with nausea and vomiting |
| chronic consequences of space flight (5) | decreased blood volume, cardiac output, RBC mass, muscle strength, and loss of Ca2+ and PO43- from bones (bones become fragile) |
| what consequences are there when returning to earth | orthostatic hypotension (cardiovascular system and baroceptor reflexes which maintain BP are not used to no gravity leading to dizziness and fainting) |