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Clinical Cardiology
Clinical Cardiology, Oxford Handbook of Clinical Diagnosis
| Question | Answer |
|---|---|
| Probability of MI if troponin is normal after 12 hours? | <0.3% |
| Elevated troponin indicates what? | Muscle necrosis up to 2 weeks before |
| ST segment elevation on ECG suggests? | Current ischaemia (or rarely ventricular aneurysm) |
| What is the blanket term for angina and infarction? | Acute coronary syndrome |
| Why are serial ECGs and enzymes important? | To distinguish angina from infarction |
| Typical features of angina pain? | Central pain ± radiating, intermittent, relieved by rest/nitrates, <30 minutes |
| How is angina confirmed? | No troponin rise after 12 hours, no ST elevation |
| What relieves angina pain? | Rest or nitrates |
| Typical features of STEMI pain? | Continuous >30 minutes, not relieved by rest/nitrates |
| ECG criteria for STEMI? | ST elevation ≥1mm in limb leads or ≥2mm in chest leads |
| What does troponin elevation confirm in STEMI? | Muscle necrosis episode up to 2 weeks before |
| Why is ST elevation sufficient for thrombolysis? | Indicates transmural ischaemia |
| Typical features of NSTEMI pain? | Continuous >30 minutes, not relieved by rest/nitrates |
| How is NSTEMI confirmed? | Elevated troponins after 12 hours, ST/T changes but no ST elevation |
| What ECG changes are seen in NSTEMI? | ST depression, T wave inversion |
| Typical features of oesophagitis pain? | Pain when supine or after food, relieved by antacids |
| How is oesophagitis confirmed? | Normal troponin, normal ECG, improvement with antacids, endoscopy evidence |
| Key differentiator between oesophagitis and angina? | Relief with antacids vs nitrates |
| Clinical features of pulmonary embolus? | Chest pain, abrupt dyspnea, cyanosis, tachycardia, loud P2, DVT risk factors |
| How is pulmonary embolus confirmed? | V/Q mismatch or CT pulmonary angiogram showing clot |
| What heart sound is accentuated in pulmonary embolus? | Loud second sound in pulmonary area |
| Clinical features of pneumothorax? | Abrupt chest pain, breathlessness, hyperresonance on percussion |
| How is pneumothorax confirmed? | Expiration CXR showing dark field with loss of lung markings outside sharp lung edge |
| What physical exam finding suggests pneumothorax? | Resonance to percussion over affected site |
| Clinical features of aortic dissection? | Tearing pain radiating to back, absent pulses, early diastolic murmur, hypotension |
| How is aortic dissection confirmed? | CT/MRI showing loss of single clear lumen |
| What chest X-ray finding suggests aortic dissection? | Wide mediastinal shadow |
| Clinical features of chest wall pain? | Pain and tenderness on chest wall movement/twisting |
| How is chest wall pain confirmed? | Normal troponin/CK-MB, normal ECG, response to rest/analgesics |
| Key differentiator between chest wall pain and cardiac pain? | Localized tenderness and reproducibility with movement |