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WEEK 18:

Lung pathology - Restrictive Lung Disease:

QuestionAnswer
restrictive lung disease types (2) acute and chronic
acute restrictive lung disease ARDS (acute respiratory distress syndrome)
chronic restrictive lung disease (2) pulmonary fibrosis (sarcoidosis) + pneumoconioses
pneumoconiosis group of fibrosing diseases resulting from exposure of toxic particles usually from work over time even after exposures stopped eg asbestos or coal dust
what can pleura be affected by (3) infection, effusion, and tumour
infection pathology of pleura pleurisy leading to sharp pain when breathing deeply, coughing, sneezing, and a dry sound on auscultation on one side
effusion/ tumour pathology of pleura transudate/ exudate in pleural cavity, or a local tumour invasion or metastases from lung/ breast carcinomas via lymphatics
pleural effusion causes (5) pneumonia, cancer, congestive heart failure, kidney disease, and liver disease
symptoms of pleural effusion (4) SOB, chest pain when breathing deeply, fever and cough
treatment for pleural effusion antibiotics or chest drain
restrictive lung disease group of disorders affecting lung connective tissue leading to damage of pneumocytes and capillaries which affect gas exchange and result in hypoxia
how does fibrosis lead to decreased compliance inflammation of alveolar walls activate inflammatory cells which damage pneumocytes which causes proliferation of type II pneumocytes. These attract more macrophages which secrete fibroblasts. Fibroblasts lay down collagen
immune response in pneumoconioses is stimulated by particles/ macrophages travelling in lymphatics
what do lesions in lungs due to penumoconioses look like lesions consist of nodules with particles and macrophages and dense collagen
Created by: kablooey
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