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WEEK 6:
Synaptic Transmission
| Question | Answer |
|---|---|
| terminal bouton | end of axon |
| types of synapses | axo-dendritic, axo-axonic, axo-somatic |
| axo-dendritic | axon -> dendrite |
| axo-axonic | axon -> axon |
| axo-somatic | axon -> body |
| neurotransmitters | endogenous chemical that enables neurotransmission |
| endogenous | made in own body |
| types of neurotransmitters | |
| ionotropic receptor | outside + fast, ligand gated ion channel- ligand binds + opens ion channel in post synaptic membrane (depolarising + change ionic permeabilty) |
| metabotropic receptor | inside + cascade effect (slow) |
| excitatory ionotrophic event | |
| central neurotransmitter in excitatory ionotrophic event | |
| peripheral neurotransmitter in excitatory ionotrophic event | |
| EPSP in words | excitatory postsynaptic potential |
| EPSP | |
| ISPS in words | inhibitory postsynaptic potential |
| amplitudes of EPSP/IPSP | add EPSP/IPSP together to make stronger EPSP/IPSP |
| temporal summation | 2 at one time |
| what does AP depend on | reaching threshold |
| integration | |
| spatial summation | close together + added together |
| ISPS | |
| GABA | |
| ionotropic GABA | |
| metabotropic GABA | |
| functions of GABA | |
| diazepam | |
| noradrenaline reuptake | |
| noradrenaline degradation | |
| serotonin reuptake | |
| dopamine reuptake | |
| dopamine degradation |