F = 100 x (AUC extravascular / AUC IV) x (Dose IV / Dose extravascular)

Volume of Distribution

Vd = Amount of drug in body / plasma concentration of drug

Cl = (F x dose)/AUC Cl = ke x Vd

Predicting Drug Concentrations

Cmin = Cmax x e^-kt ke = [ln(Cmax/Cmin)] / t

LD = (Desired Concentration x Vd) / F

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Required Formulas 3

Required Formulas - Pharmacokinetics

Term	Definition
Bioavailability	F = 100 x (AUC extravascular / AUC IV) x (Dose IV / Dose extravascular)
Volume of Distribution	Vd = Amount of drug in body / plasma concentration of drug
Clearance	Cl = (F x dose)/AUC Cl = ke x Vd
Elimination Rate Constant	ke = Cl / Vd
Predicting Drug Concentrations	Cmin = Cmax x e^-kt ke = [ln(Cmax/Cmin)] / t
Half- Life	T -1/2 = 0.693 / ke
Loading Dose	LD = (Desired Concentration x Vd) / F