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HSII Chpt. 6 (Pt. 2)
Hematology & Immunology Important Terms to Know
| albumin | Plasma proteins too large to pass through the wall of a blood vessel. Most common protein in blood. |
| antigen | Any substance (as an immunogen) foreign to the body that evokes an immune response. |
| complement | A group of nine proteins that activate each other. |
| ecchymoses | Hemorrhages larger than petechiae. |
| embolus | A thrombus (blood clot) that has broken free and travels through the circulatory system. |
| histamine | A substance which dilates blood vessels and increases blood flow. |
| Hodgkin’s lymphoma | The most common type of lymphoma. |
| immune | Not susceptible or responsive. |
| index (plural: indices) | A ratio or other number derived from a series of observations and used as an indicator or measure |
| interferon | Immune response chemicals which stimulates production of an antiviral substance. |
| lymph | A clear, watery, sometimes faintly yellowish fluid derived from body tissues that contains white blood cells and circulates throughout the lymphatic system, returning to the venous bloodstream through the thoracic duct. |
| mean | Something having a position, quality, or condition midway between extremes; a medium. |
| node | A discrete mass of one kind of tissue enclosed in tissue of a different kind. |
| nucleoside | Encapsulated structures that are round, oval or bean shaped. |
| pernicious | Highly injurious or destructive. |
| petechiae | small, pinpoint hemorrhages. |
| plasma | A clear straw-colored liquid that makes up 55% of the blood. |
| plasminogen | A cell fragment active in the blood clotting process. |
| platelet | (also thrombocyte) A minute, irregularly shaped, cytoplasmic body found in blood plasma that promotes blood clotting and has no definite nucleus, no DNA, and no hemoglobin. |
| purpura | Any of several hemorrhagic states characterized by patches of purplish discoloration resulting from extravasation of blood into the skin and mucous membranes. |
| serum | The fluid portion of plasma that remains when clotting factors in plasma form a blood clot. |
| spleen | A rounded lymphoid organ, located in the left upper quadrant of the abdomen. |
| stasis | A slowing or stoppage of the normal flow of a bodily fluid or semifluid. |
| thalassemia | Inherited genetic abnormality that affects the synthesis of the globin in hemoglobin. |
| thrombus (pl. thrombi) | Blood clot |
| thymus | A lymphoid organ with a pink color and a grainy consistency. |
| transcriptase | A polymerase that catalyzes the formation of RNA from a DNA template in the process of transcription. |
| vaccine | A preparation of killed microorganisms, living attenuated organisms, or living fully virulent organisms that is administered to produce or artificially increase immunity to a particular disease. |
| Hematopoiesis | Blood cell production process. Usually occurs in the red marrow of long bones and flat bones. Each cell or cell fragment begins in the marrow as a very immature stem cell. |
| Leukocytes (WBCs) | Five types of leukocytes, which are identified by granules and nucleus. Categorized by granulocytes and agranulocytes. Granulocytes have granules in the cytoplasm and agranulocytes don't have granules. |
| Neutrophils | Most common: make up 54-62% of leukocytes Granulocytes with many large granules that remain neutral when stained. Nucleus has many lobes and segments. Develop in red marrow, eventually become immature band or stab. |
| Eosinophils | Makes up 1-3% of leukocytes. Granulocytes with many large granules. Granules stain pink when exposed to eosin. Nucleus has 2 lobes. Develop in red marrow from stem cells. |
| Basophil | Least common: makes up 0.5-1% of leukocytes. Granulocytes with many large granules. Granules stain blue when exposed to hematoxylin. Nucleus has more than one lobe. Develop from stem cells in red marrow. |
| Lymphocyte | Makes up 25-335% of leukocytes. Agranulocytes. Nucleus fills most of cell. Develop from lymphoblasts. |
| Monocytes | Make up 3-7% of leukocytes. Largest type of leukocytes, agranulocytes. Nucleus is large and shaped like a kidney bean. Develop in marrow from stem cells and mature in stages. |
| Thrombocytes (Platelets) (Thromb/o- = Blood clot) (-cyte = cell) |