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Anatomia Patologica

Cardiovascolare

QuestionAnswer
Cos'è la cardiomiopatia ipertrofica? Ipertrofia miocardica . Miocardio ventricolare sx scarsamente deformabile che conduce a un anomalo riempimento diastolico  In circa un terzo dei casi, intermittente ostruzione all’efflusso ventricolare
Mutazioni che causano cardiomiopatia ipertrofica? Le mutazioni che provocano la CMPI si trovano spesso nei geni che codificano per la proteina C legante la miosina (MYBP-C) o per la catena pesante della β-miosina (β-MHC/MYH7), seguite in ordine di frequenza dai geni per la TnI cardiaca, TnT e α-tropomios
Meccanismo alla base della cardiomiopatia ipertrofica? Benché il preciso meccanismo secondo il quale queste mutazioni causano la CMPI non sia chiaro, le prove a disposizione suggeriscono che derivi da un difetto nel trasferimento di energia dalla sua sorgente (mitocondri) al punto in cui viene utilizzata (sa
Cosa hanno spesso i pazienti aventi endomiocardite di Loeffler, in associazione? Molti pazienti con endomiocardite di Loeffler presentano una malattia mieloproliferativa associata a riarrangiamento cromosomico del recettore del fattore di crescita derivato dalle piastrine di tipo α o β
Created by: Giovi00
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