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hormonal/glucose reg
final patho
| Term | Definition |
|---|---|
| Hormone produced in the hypothalamus | Corticotrophin-releasing hormone, dopamine, growth hormone, somatostatin, gonadotropin-releasing hormone, thyrotrophin-releasing hormone |
| Hormone produced by the hypothalamus | ADH (vasopressin) and oxytocin |
| Anterior Pituitary hormones | ACTH, GH, TSH, FSH, LH, Prolactin |
| Posterior Pituitary hormones | ADH, Oxytocin |
| ACTH: adrenocorticotropic hormone | release of corticosteroids |
| GH: growth horomone | triggers growth |
| TSH: thyroid-stimulating | Tells thyroid how much hormone to make |
| FSH: follicle stimulation | stimulates ovarian follicles and somniferous tubules |
| LH: luteinizing hormone | produce of androgen (testosterone) |
| Prolactin | Causes breast to grow and make milk for pregnancy |
| ADH: Anti-diuretic | decrease diuresis by controlling renal function |
| Oxytocin: | stimulates contraction of uterus |
| Hypopituitarism | GH deficiency |
| Hyperpituitarism | Acromegaly; excess GH before closure resulting in overgrowth of long bones |
| Diabetes Insipidus | Results from hyposecretion of ADH |
| s/s diabetes insipidus | Hypovolemia, Tachycardia, Decreased BP |
| diabetes insipidus cardinal signs | Polyuria, Polydipsia. (NOT POLYPHAGIA) |
| Type 1 and 2 Diabetes Mellitus requires what? | serum glucose |
| SIADH | Syndrome of inappropriate Antidiuretics Hormone |
| SIADH is produced by | hypersecretion of posterior pituitary, increased ADH |
| s/s of SIADH | fluid retention, hypotonicity (low Na), Anorexia, irritable, personality changes |
| Thyroid hormone regulates | BMR (basal metabolic rate) |
| Thyroid secretes what 2 hormones? | T3 (triiodothyronine) and T4 (thyroxine) |
| s/s of irregular thyroid function | decelerated growth, constipated, sleepy, dry skin, sparse hair, periorbital edema |
| Goiter | Hypertrophy of thyroid gland |
| Hyperthyroidism | Grave's disease |
| Hyperthyroidism is an enlarged? | Thyroid gland and exophthalmos |
| Hypothyroid levels | T3 and T4 decreased, TSH increased |
| Hyperthyroid levels | T3 and T4 increased, TSH decreased |
| What medicine is given for Hypothyroidism | Synthroid |
| What medicine is given for Hyperthyroidism | PTU |
| Parathyroid glands secrete | PTH (parathyroid hormone) |
| Function of PTH | Increasing release of Ca and phosphate from bone Increasing absorption of Ca and excretion of phosphate by the kidneys Promote Ca absorption in GI tract |
| Adrenal cortex secretes 3 groups of steroids: | Glucocorticoids, Mineralocorticoids, Sex steroids |
| Glucocorticoids | Cortisol and corticosterone |
| Mineralcorticoids | aldosterone |
| Sex steroids | androgens, estrogens, progestins |
| Cushing's syndrome | excessive cortisol |
| Is Cushing's curable? | reversible once steroids are discontinued |
| s/s of cushing's | Mood face, red cheeks, excessive hair growth, weight gain, red striae, |
| Diabetes Mellitus | deficiency of insulin; glucose is unable to enter cell and stays in blood causing hyperglycemia |
| Glycosuria | glucose in urine |
| glycogenesis | cells breakdown protein for conversion to glucose by the liver |
| DM type 1: Ketoacidosis | severe insulin deficiency; glucose unavailable for cellular metabolism |
| ketonuria | ketone in urine |
| Which acid-base imbalance might you see Kussmaul respirations ad hyperkalemia? | Metabolic acidosis |
| Long-term complications of DM | macrovascular disease and neuropathy |
| Glucose monitoring goal range | 80-120 mg/dL |
| CM of DM type 1 | deficiency of insulin: destruction of Beta cells; cannot be prevented and requires insulin for life |
| CM of DM type 2 | can't be prevented, body lacks insulin, required insulin when needed |
| S/s for type 1 and 2 | thirst, frequent urination, blurred vision |
| What lab value is used to determine DM | fasting blood sugar |
| Kussmaul breathing | deep labored breathing associated with metabolic acidosis and diabetes |