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P3 ID 3-4 Drug quiz

Generic Brand Pharmacological Category Common Indication Activity againstKey Side Effects US Boxed Warning Other Notes
clindamycin (PO,IV) Cleocin Lincosamide antibiotic SSTI, pharyngitis MRSA diarrhea, Clostridioides difficile diarrhea Clostridioides difficile-associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including clindamycin, and may range in severity from mild diarrhea to fatal colitis
sulfamethoxazole and trimethoprim (PO,IV) Bactrim, Bactrim DS Sulfonamide antibiotic SSTI MRSA nausea, vomiting, diarrhea, skin rashes (rarely SJS or TEN), hyperkalemia, increased serum creatinine, fixed ratio (5:1) of sulfamethoxazole and trimethoprim; dosing based on trimethoprim component
nitrofurantoin (PO,) Macrobid Urinary antibiotic Cystitis, Escherichia coli nausea, pulmonary fibrosis (chronic use)
gentamicin (IV) n/a Aminoglycoside antibiotic HAP, pyelonephritis, neonatal sepsis Pseudomonas aeruginosa, Escherichia coli nephrotoxicity, vancomycin
vancomycin (IV, PO) Vancocin Glycopeptide antibiotic IV: SSTI, HAP, meningitis, endocarditis, CRBSI PO: CDI MRSA, Clostridioides difficile nephrotoxicity, ototoxicity
metronidazole(PO) Flagyl Antibiotic Anaerobic infections, CDI, Bacteroides species, Clostridium difficile nausea, metallic taste, alcohol intolerance, peripheral neuropathy (long-term use)
mupirocin (Topical) Bactroban Antibiotic MRSA decolonization Topical MRSA N/A
terbinafine(PO, topical -OTC) Lamisil Allylamine antifungal Onychomycosis Fungal species nausea, abdominal pain, diarrhea, elevated hepatic transaminases, headache
acyclovir (PO,IV) Zovirax Antiviral Herpes Simplex Virus Herpes simplex virus nausea, increased hepatic transaminases, crystalluria Vesicant
fluconazole (PO,IV) Diflucan Azole antifungal Vulvovaginal candidiasis, oropharyngeal candidiasis Vulvovaginal candidiasis, oropharyngeal candidiasis nausea, abdominal pain, diarrhea, QTc prolongation, elevated hepatic transaminases
ketoconazole (PO, topical *) Nizoral Azole antifungal Fungal infections Fungal infections nausea, abdominal pain, diarrhea, QTc prolongation, increased hepatic transaminases serious hepatotoxicity, including cases with a fatal outcome or requiring liver transplantation, have occurred; may cause QTc prolongation and drug interactions leading to QTc prolongation
oseltamivir (PO) Tamiflu Neuraminidase inhibitor antiviral Influenza H. influenzea nausea, vomiting, neuropsychiatric events (i.e., confusion, delirium, hallucinations) in pediatric patients (rare)
nystatin(PO) N/A Polyene antifungal Oropharyngeal candidiasis Fungal species N/A only use oral solutions for thrush
micafungin (IV) Mycamine Echinocandin antifungal Invasive candidiasis Fungal species N/A
betamethasone and clotrimazole(Topical) Lotrisone Glucocorticoid and azole antifungal Cutaneous fungal infections Fungal species burning, itching, dryness, skin atrophy do not use for diaper dermatitis; adrenal suppression with long-term use over large areas of skin
valacyclovir(PO) Valtrex Antiviral Herpes Simplex Virus Herpes Simplex Virus nausea, increased hepatic transaminases
nystatin(topical) Nystop Polyene antifungal Cutaneous and mucocutaneous fungal infections Fungal species burning, itching only use oral solutions for thrush
Created by: ChristopherMoise
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