click below
click below
Normal Size Small Size show me how
Nutrition
Surgery I
| Question | Answer |
|---|---|
| Prevalence of malnutrition in hospitalized pts | 15-50% |
| Cachexia | Loss of wt, appetite, mx atrophy, & weakness; usu signifies an underlying dz |
| Kwashiorkor | acute visceral protein depletion. Usually children |
| Marasmus | Simple starvation |
| Body composition is divided into: | fat mass & lean body mass |
| Early vs late starvation | Early: proteolysis is dominant; late: body adapts to conserve protein, fat becomes major energy source |
| Fat mass: % of total body wt (TBW)? | 25-35% TBW |
| Lean mass: % of total body wt (TBW)? | 40% TBW |
| Lean body mass composition | 60% skeletal mx; 20% RBC & conn tissue; 20% organ tissue |
| peripheral neuropathy may be due to deficiencies in: | niacin, thiamine, vitamin B6, vitamin B12 |
| Primary means of measuring protein (nitrogen) balance in body: | urine urea nitrogen |
| marker for significant nutritional depletion: body wt that is: | less than 90% of the usual or ideal body wt |
| Percentage of total body protein contained in skeletal muscle | 60% (this is major site of protein catabolism during starvation and/or illness) |
| Most widely used biochemical marker of muscle mass | 24 hr urine creatinine |
| Creatinine is: | degradation product of creatine, an energy storage compound located in skeletal muscle |
| Most common test to measure breakdown of protein | Urinary urea nitrogen |
| Lean body mass represents: | the critical cellular mass necessary for cellular structure & function; 40% of total body weight; Depletion is severe insult & defines pt morbidity & mortality |
| Skin fold thickness is a reasonable estimate of adipose caloric reserves because: | 50% total body fat is subQ; fat is lost proportionally from central stores and subcutaneous tissue |
| Creatinine- height index (CHI) level that defines skeletal muscle depletion | CHI < 80% |
| Serum albumin half life: | 18 - 20 d |
| Normal serum albumin = | > 3.5 g/dL |
| Serum prealbumin: Sensitive to: | acute changes in nutrient intake |
| Basal (resting) Energy Expenditure (BEE) is calculated by using: | Harris-Benedict equation |
| In pts who have sustained injuries, calculate resting energy expenditure by: | bedside indirect calorimetry to determine VO2 and VCO2 (Weir Formula) |
| Catabolic Index (CI): measures: | severity of stress (CI = UUN – 0.5 (dietary nitrogen intake) + 3 g) |
| Routes for delivering nutrition | Enteral. Enteral plus venous. Central venous access (eg, TPN) |
| Preferred route for delivering nutrition | Enteral |
| Primary fuel source for body | Carbohydrates. Metabolized as glucose, stored as glycogen (both depleted from liver/muscle stores in 24-36h of fasting, then fat & protein used) |
| Essential fatty acids are: | linoleic acid and linolenic acid |
| Fat metabolism yields: | fatty acids, glycerol, and ketone bodies (ketone bodies used as fuel during starvation) |
| Daily protein requirement in healthy adult | 0.8 gm/kg/day (minimum 0.54 gm/kg/day). Up to 2x that in stressed pt |