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cholelitasis
deep questions
| Question | Answer |
|---|---|
| Types of gallstones | 1; cholesterol 2; crystalline cholesterol monohydrate 3; bilirubin |
| Patholgy on the basis of bile acids and salts | Excessive cholesterol->bile salts and bile acids cannot emulsify it->stasis ->water gets absorbed ->mucus secretion->stone formation |
| Pathology on the Basis of extravascular hameorrhage( round worm, Clonorchis sinensis) | Excessive bilirubin -> stasis->calcium deposition ->stones formation |
| morphology of cholesterol salts | yellow, smooth surface, round, firm |
| morphology of bilirubin salts | Black, fragile, round to oval, indicate sterility of gallbladder |
| cholesterol+ bilirubin stones | yellow+ black |
| brown stones | stones with superadded infection |
| Sx | sharp and sudden RUQ pain, sense of fullness, shoulder blade pain, nausea, vomiting |
| complications | biliary tract infections, biliary colic, jaundice, acute cholecystitis, chronic cholecystitis, gallstone ileus, gallbladder cancer |