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Ped Rheum Boards
Adaptive Immune Cells
Question | Answer |
---|---|
production of Ab | B cell |
production of IFN gamma to activate macrophages to produce reactive nitrogen species and kill intracellular bacteria and fungi | Th1 CD4+ T cell |
- production of IL4 to stimulate Ab production, in particular IgE - production of IL5 to stimulate differentiation and activation of eosinophils - defense against helminth infection, but can also cause allergy | Th2 CD4+ T cell |
- production of IL17, which induces neutrophil-rich inflammation - defense against extracellular bacteria and fungi | Th17 CD4+ T cell |
- expression of CTLA4 and TGF beta to suppress autoreactive T cells - helps to maintain peripheral tolerance | Treg CD4+ T cell |
lysis of virus-infected cells expressing viral Ag | CD8+ T cell |