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Patholophysiology

QuestionAnswer
Pathophys of VTE in pts with cancer Tissue factor (TF) forms a complex with factor VII to activate factor IX and factor X, leads to coag.
Types of cancer in which tissue factor is seen: sarcoma, melanoma, neuroblastoma, lymphoma, pancreatic ca, colorectal ca, ovarian ca (esp clear cell), APL
4 types of diffusion across cell membranes Mediated transport; facilitated diffusion; primary active transport; secondary active transport
3 types of facilitated diffusion ligand-gated, voltage-gated, mechanically-gated
Mechanism in mediated transport transporter proteins change conformation
Distinction between primary and secondary active transport Primary uses ATP (eg, the Na+/K+-ATPase pump), and secondary relies on electrochemical gradient
Created by: Abarnard
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