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Path-Inf. Skin Dis
Keep it simple
| Question | Answer |
|---|---|
| spongiotic dermatitis | eczema(boiling over) increase in inflammation resulting in widened spaced filled with fluid b/t keratinocytes via lymphocytes and macrophages |
| Allergic contact dermatitis | es. poison ivy treat with corticosteroids |
| atopic dermatitis | more chronic and persistant spongiotic dermatitis via inf. or irritation |
| Foliculitis | genetic and androgenic influence keratin and sebum clog follicles resulting in proprionibacterium acnes resulting in open and closed comedones (white and blackheads) |
| Leukocytoclastic vasculitis | immune complexes lodge in the vascular walls (venule) resulting in complement cascade and damage with palpable purpura |
| where is leukocytoclastic vasculitis found | on the lower extremities, GI, Kidney, and CNS |
| Erythema Multiform | eruption of the skin |
| Steven Johnson Syndrome | TEN (toxic epidermal necrolysis) mucus membrane involvement and shedding of the skin via Herpes, infectious agents, and drugs |
| what is the pathology of Steven johnson syndrome | 1) degeneration of the basilar layer 2) eosinophilic apoptotic bodies 3) perivascular lymphocyte infiltrate |
| Impetigo | Staph and Strep infections honey colored cysts can lead to post strep glomerulonephritis |
| how does impetigo happen | neutrophils aggregate below the statum corneum |
| syphillis treponema pallidum | Chancre (painless) resolves in 6 weeks followed by condyloma lata and maculopapular eruptions of palm and soles and then endarteritis and ischemia |
| what are the systemic lesions associated with syphilis | liver, mucus membrane, meninges, |
| Gumma | characteristic nodules of tertiary syphilis |
| what stain do you use to see spirochetes | warthin starry stain |
| what are the infiltrative cells with syphilis infections | plasma cells |
| Verrucae | warts via HPV can spread with superficial trauma |
| Verruca vularis | most familiar can find anywhere with a rough surface |
| verruca plantaris | flat small lesion that appears as multiples on the feet |
| condyloma accuminatum | papillary lesion in anogenital region verucae are generally benign |
| Bowenoid Paulosis and Epidermodysplasia verruciformis | precancerous lesions from HPV (think HPV and koilocytes when hyou see verruciformis) just remember bowenoid HPV |
| Molluscum contagiosus | flesh colered papules with central keratotic core spread via pox virus |
| moluscum bodies and inclusion bodies | molluscum contagiosum |
| varicella zooster virus and Herpes 1 and 2 | all herpes from dorsal root ganglia confined within the DERMATOME that root supplies |
| multiple gun metal gray nuclei | Herpes and varicella zooster |
| Superficial Fungal infection Dermatophiytes | superficial red scaly patches named by region |
| tinea capitus | a superficial fungal infection that can cause hair loss |
| candida albicans | papules and pustules in the intertriginous area (those that rub together) |
| Malassezia furfur (hypal form of pityrosporum | cause white scaly patches on the trunk |
| malasseazia | minimal change with multiple yeast forms |
| dermaphytes and candida and malassezia furfur are all | superficial fungal infections |
| how makes yeast out of the superficial fungal infections | candida and malassezia |
| who of the superficial fungal infections makes hyphea | dermophytes (candida make pseudohyphea |
| scabies | transmitted via an arthropod bite/sting |
| sarcoptes scabiei | female burrows in finger webs and genitals with intense itching |
Created by:
jmuame03
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