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vagina on

Clear cell carcinoma (vaginal) unlike ovarian this arises in young women whose mothers used DES (glands of clear cells that HOBNOB (nucleus protrudes out))
Embryonal Rhabdomyosarcoma sarcoma of primitive skeletal muscle cells in children
Rhabdomyosarcoma botryoid tends to occur in vagina and bladder (grape like) protrudes from the vagina with cambian growth patter (treelike) 50% 5year
Endocervical Polyp BENIGN cervical lesion from the os can cause post coital bleeding (endothelium over thich walled blood vessel
Adenocarcinoma in situ Premalignant cervical lesion- in transformation zone associated with HPV, nuclear enlargement with loss of cytoplasm
HSV2 a virus that causes non-painful vesicles and shallow excruciatign ulcerations
Vulvular cysts Bartholin’s Gland hard to palpitation hiding behind the labia minora may mimick malignancy
Non-infectious cervicitis can be caused by? chemical, mechanical damage but is often asymptomatic with infiltrate and squamous metaplasia
Lichensclerosis et Atrophicus common cause of white changes in the vulva most often in post menopausal women may be painful Parchment paper like lesions
Padget’s disease red eczematous with irregular borders in older women this is an intraepithelial proliferation of Malignant gland like cells that rarely invade below stroma thought to be sebaceous gland
Melanoma padgetoid spread of nest cells (10% of vulvar malignancies)
Acute endometriosis often s. aureus, strep or gonorrhea that occurs postpartum or post abortion (remaining placental parts)
Chronic endometriosis may be due to infections (chlam or gon) or trauma from IUD or leiomyomata emboli
Endometrial Polyp common benign may cause irregular bleeding
Adenomyosis when ENDOMETRIAL gland is found within the MYOMETRIUM
Endometrial Hyperplasia in perimenopausal women as a result of increased estrogen due to proliferation of the glands
Endometrial Adenocarcinoma 4th most frequent cancer in women with excess estrogen being the main association based on obesity, therapy, age of menopause, anovulation, tamoxifen)
Endometrioid Adenocarcinoma hyperplasial version of endometrial adenocarcinoma
Uterine papillary serous carcinoma worse prognosis atrophic version of endometrial adenocarcinoma
Leiomyomas benign fibroids MOST COMMON NEOPLASM IN WOMEN (25% of premenopausal)
Leiomyosarcomas Malignant mets to lung liver and brain within 2 years of diagnosis unlike leiomyomas they have focal hemorrhage necrosis and cytological atypia
Malignant Mixed Mullerian Tumor often in elderly women with polypoid mass coming from the endometrium and protruding through the cervix (poor prog - mix of leiomyosarcoma, rhabdomyosarcoma and osteosarcoma)
Fallopian tube diseases acute salpingitis, endometriosis, primary fallopian tube carcinoma
acute salpingitis PID from chlam, gon, E.Coli, myoplasma, and anaerobic bacteria can progress to infertility and ectopic pregnancy risk
endometriosis endometrial tissue outside of the uterus in the fallopian tube cycles normally
how do you get endometriosis metaplasia, benign metastaisis, and backwash
Primary Fallopian Tube Carcinoma rare <1% of malignancies looks like the serous papilary tumor of the ovary
what are the benign cysts of the ovary follicular, luteal, and polycystic ovarian
folicular cysts benign cysts in the ovary composed of granulose cells and outer thecal cells with high estrogen resulting in endometrial hyperplasia and bleeding
Luteal cysts benign cysts in the ovary from persistant corpus albicanta (especially during pregnancy) that secretes progesterone resulting in menstral irregularities and a mass
Polycystic ovarian disease Stein Leventhal disease of women in their 20s and 30s characterized by a LH surge which increases estrogen and testosterone (insulin resistance, hierutism, infertility, irregular cycles
what are the three neoplasms of the ovary surface, sex cord, and germ cell
what are the surface neoplasms of the ovary serous, mucinous, endometrioid, clear cell and brenners
Serous papilloma a surface neoplasm of the ovary which may have PAPILLOMA BODIES with ciliated columnar cells can be bilateral and is often malignant 5 yr<50%
two types of serous papilloma surface neoplasm of the ovary Adenoma (smooth) and carcinoma (cystic and solid)
Mucinous tumor surface neoplasm of the ovary often multifocal filled with mucin and made of intestinal or endocervical cells with goblets
Pseudomyxoma peritoneii Jelly Belly- mucin in the abdominal cavity from the appendicular or ovarian primary but even though you can remove it the 5 year is still only 5% due to adhesion and abcess
endometrioid tumor surface neoplasm of the ovary benign with 15% being a primary with another primary in the uterus
Clear Cell carcinoma of the ovary this presents in older women it is a cyst adenoma with lots of cytoplasm and hobnob nuclei
Brenner's Most benign but you do get malignant Bladder like
waht are the ovarian germ cells tumors of the ovary Teratoma, Gysgerminoma, Yolk Sac, Embryonal, Choriocarcinoma
Teratoma of the Ovary dermoid cysts with tissue from different layers from various layers may be mature (cystic) or immature (solid) may go malignant but not likely
gliomatosis peritonei when there is a neural teratoma that ruptures into the peritonium
Dysgerminoma Malignant tumor of the ovary (like the testicular seminoma) that forms in women in their 20s and 30s it is unilateral with an excellent prognosis and is radiosensitive ALSO SECRETES B-HCG (why it is like testicular seminoma)
Yolk Sac Tumor of the Ovary Malignant Endometrial Sinus Tumor with Schiller Duvall Bodies in adolescent and young women secretes alpha fetal protein
Created by: jmuame03