Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Vagina, Vulva, Cervi
keep it simple
| Question | Answer |
|---|---|
| Clear cell carcinoma (vaginal) | unlike ovarian this arises in young women whose mothers used DES (glands of clear cells that HOBNOB (nucleus protrudes out)) |
| Embryonal Rhabdomyosarcoma | sarcoma of primitive skeletal muscle cells in children |
| Rhabdomyosarcoma botryoid | tends to occur in vagina and bladder (grape like) protrudes from the vagina with cambian growth patter (treelike) 50% 5year |
| Endocervical Polyp | BENIGN cervical lesion from the os can cause post coital bleeding (endothelium over thich walled blood vessel |
| Adenocarcinoma in situ | Premalignant cervical lesion- in transformation zone associated with HPV, nuclear enlargement with loss of cytoplasm |
| what is the main difference between low and high risk HPV | high risk inserts itself into the genome |
| high risk HPV? low | high 16,18, 31,33 Low 8 and 11 |
| What CIN gradings are high grade | CIN 2 and CIN 3 |
| what percent of untreated high grade dysplasias progress to SCC | 70% |
| two mechanisms of high risk HPV cancer causing | insert and inactivate p53 or activate retinoblastoma (uncontrolled DNA proliferation) |
| what is the histiological apperance of chlamydia | follicular cervicitis |
| what are two complications of chlamydia | endometritis (40%) and salpingitis (11%) |
| Post chlamydia sequelae | PID, Tubal infertility, neonate pneumonia |
| HSV2 | a virus that causes non-painful vesicles and shallow excruciatign ulcerations |
| what are the three Ms seen in late Herpes Infections | Multinucleation, Margination(clear around nucleus) and Molding (push against each other) |
| what happens if herpes is passes onto the child during birth | encephalitis, neurological damage, mental retardation |
| Non-infectious cervicitis can be caused by? | chemical, mechanical damage but is often asymptomatic with infiltrate and squamous metaplasia |
| Vulvular cysts Bartholin's Gland | hard to palpitation hiding behind the labia minora may mimick malignancy |
| Lichensclerosis et Atrophicus | common cause of white changes in the vulva most often in post menopausal women may be painful Parchment paper like lesions |
| what is the NON HPV squamous cell carcinoma | Lichen sclerosis et atrophicus |
| Padget's disease | red eczematous with irregular borders in older women this is an intraepithelial proliferation of Malignant gland like cells that rarely invade below stroma thought to be sebaceous gland |
| prognosis of padget's disease | slow progression with surgical removal being challenging due to irregular borders 15% of other women have malignancy elsewhere |
| Melanoma | padgetoid spread of nest cells (10% of vulvar malignancies) |
| survival of melanoma patients is based on | degree of invasion less than 1.5 mm great prognosis, more = 5% 5yr |
| what is micro invasive scqamous cell carcinoma | SCC of less than 3 mm this is important because there is a decreased risk of spread and excellent prognosis |
Created by:
jmuame03
Popular Medical sets