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Micro Final-1


Penicillin G+ BL-; syphilis, N.meningitidis; BL- N. gon
Ampicillin Staph/Strep, Enterobactericiae (Ecoli/Proteus mirabilis); increasing G-
Amoxicillin increasing G-, wimpy Enterobactericiae (Ecoli, P.mirabilis); Staph/Srep
Imipenem zwitterion, smallest, gram - (requires calcium something addition)
Meropenem zwitterion, smallest, gram -
Combos (Ticarcillin/Piper/Carbenicillin) HI, Moraxella catarrhalis, Neisseria, Staph aureus
B lactamase inhibitor pairing combos amox+clav; amp+sulbact
Nafcillin/Methicillin gram +, staph/strep (no gram negatives)
First Gen Cephalosporins CEPHALEXIN/CEFAZOLIN; B-lactamase + Staph (SSS-->staph/strep/surgeries) (no enterococci/no MRSA)
Sec Gen Ceph cefuroxime; cefotetan; G- bacilli (enterobactericiae (no enterobacter/no pseudo)
Thrid Gen Cephalosporins ceftazidime/cefotaxime/cefoperazone/ceftriaxone; pseudomonas, G-
Fourth Gen Cephalosporins cefepime; pseudomonas G-
Aztreonnam monobactam; G- aerobes, no anaerobes, no gram neg, no toxicity (like aminoglycosides without toxicity)
Vancomycin gram positives; no gram positive meningitis (no BBB); MRSA; no VRE; no VRSA
What are the 2 macrolides Erythromycin and Azithromycin
Erythromycin Mycoplasma, Chlamydia, Legionella, Strep (substitute for penn); upsets stomach 50s
Azithromycin 50s; mycoplasma, chlamydia, legionella, strep, HI, moraxella catarrhalis, Neisseria gon; emperic: sinusitus, otitis media, pneumonia 50s
Clindamycin G+/G- anaerobes, MSSA, Streptococci, B frag; 50s (no enterococci; no g- aerobes)
Oxazolidanones Linezolid 50s
Linezolid 50s; VRSA; VRE; enterococcus facealis; good for resistant staph, enterococci, pneumococci
Tetracycline 30s; tetra, mino, doxy; G+/G-; chlamydia, legionella, Rickettsia, Mycoplasma
Aminoglycosides 30s; gentamicin, neomycin (topical), amikacin, tobramycin, streptomycin; aerobic G-, G+ w/pen (enterococci/enterobactericiae)
Chloramphenicol chlamydia, ehrlichia, rickettsia, aplastic anemia (ER when Tetra won't work)
Quinolones Cipro, Levofloxacin--DNA gyrase inhibitors (topoisomerase)
Cirpofloxacin aerobes, FA, no anerobes, empiric CAP: Mycoplasma, M cat, chlamydia pneum, Legionella pneumophilia, Strep pnemo (no MRSA); MSSA, g- aerobes (oral pseudomonas)
oral pseudomonas cipro
Metronidazole synthetic; parasites (trich, giardia, entambeomeba; obligate anaerobes; (no propiones, no actinomyces); clostridium, pepto, bacteroides, porphrymonas, all tissues (brain ab, abd ab, C dif colitis) no aerobic (treat with second tx for anaerobic with metro)
Bactrim (TMP-SMX) aerobes, no obligate anaerobes, protozoans; UTI, otitis media, pneumocystis pneumonia (fungal), travelers diarrhea, chronic bronchitis (acute exacerbations)
pneumocystis pneumonia Bactrim
travler's diarrhea bactrim
SMX inhibits what? PABA analogue (synthetase)
TMP inhibits what? DHF reductase
Created by: HSF2