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BACT: Strep pneumo
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| Question | Answer |
|---|---|
| shape of Strep Pneumo | lancet |
| S. Pneumo is what shape | diplococci |
| B or alpha hemolytic | Alpha on s. pyrogene is B |
| how do you diagnose S. Pneumo | Blood, Optochin sensitive, Bile solubility test, Qeulling reaction |
| type of capsule | polysaccharide |
| how many serotypes are there of the strep pneumo capsule | 80 |
| Rough mutants? | lack capsule and are not virulent |
| what is pneumolysis | thiol activated hemolysis |
| Strep pneumo is the number one cause of? | community acquired pneumonia, bacteremia in infants, adult meningitis, otitis media, conjunctiva |
| Strep pneumo is number 2 cause of ? | meningitiis in kids over 2 |
| diseases caused by strep pneumo | lobar pneumonia, meningitis, otitis media, sinusitis, chronic bronchitis, conjunctiva |
| what percent of adults have S. pneumo as normal flora | 20-70% |
| how do you treat strep pneumo | B lactams penicillin( 42% resistant) so erythromycin and vanco for resistant forms |
| how can you tell strep pneumo from strep viridans | optochin sensitive = pneumo |
| how does Strep pneumo casue meningitis | bacteremia or trauma |
| vaccines for strep pneumo | pneumovax ( T ind. greater than 2) and Prevnar (Conj for those who need to use T cells kids under 2) |
| mortality of s. pneumo if treated | 25% only 5% with treatment |
| mortality of those over 50? over 70? | 30% over 50 ---- 60% over 70 |
| how does strep pneumo avoid phagocytes | kills them with pneumolysin and capsule |
| most virulent capsule | 3 |
| what percent of patients become bacteremic | 30% |