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Basic Pharmacology
Term | Definition |
---|---|
Absorption | the process of a drug taken into the body moving from the site of administration into the blood. |
Adverse Effect | the undesired and potentially harmful side effects of medications. Examples include: nausea, vomiting and hypersensitivity. |
Agonist | drugs that are attracted or bond to a receptor and cause a particular response. Example: acetylocholine |
Antagonists | type of drugs that prevent or inhibit a response; receptor blockers. |
Bioavailability | how the drug molecule reaches to the target site to exert its effects. |
Biotechnology | using the concepts of genetic engineering and recombinant DNA technology to create drugs. |
Biotransformation | the process of changing lipid-soluble drug molecules into water-soluble molecules for excretion. Commonly occurs in the liver. |
Bolus | given all at once. |
Contraindication | reasons or situations where a drug should not be given or used. |
Distribution | the process where the circulatory system transports the drug throughout the body and drug molecules diffuse in the bloodstream. |
Duration | time between onset of a drug and its disappearance. |
Emulsion | type of liquid; a mixture of oil and water bound together with an emulsifier. |
Enteral | route of administration; drug taken into the GI tract primarily orally. |
Excretion | the process of drug molecules leaving the body; via bile, feces, skin, and urine. |
Hypersensitivity | an adverse effect from previous exposure to the drug; symptoms can range from mild to severe. |
Idiosyncratic effect | when the reason behind an adverse reaction is unknown; rare and unpredictable. |
Indication | the purpose of giving a medication. |
Local effect | where the medication works at the site of application. |
Onset | time between administration and and first appearance of effect. |
Parenteral | any route of administration except the GI tract; examples include; topical, subcutaneous, IV. |
Pharmacodynamics | the study how drugs affect the body. |
Pharmacokinetics | the study of how the body processes drugs; absorption, distribution, biotransformation, excretion. |
Plasma protein binding | drug molecules that bind to proteins in blood plasma, usually nonspecific and competitive. |
Reconstituted | powdered medications that must be mixed with liquid to form a solution prior to administration. |
Side effect | predictable but unintended effect of a drug. |
Solubility | the ability of a drug to dissolve. |
Solution | the mixture of drug molecules in a solvent. |
Suspension | undissolved drug particles floating in a liquid. |
Synergist | a drug that enhances the effect of another drug. |
Systemic effect | the effect of a drug through out the entire body. |
Topical | route of administration; applied directly to target site. |
Controlled substances | certain medications; scheduled into five classes and enforced by the DEA; the Controlled Substance Act was passed in 1970. |
Narcotics | when administered hospitals must keep records of amount used, date, patient, who administered the medication, and who obtained the medication. |
DEA | Drug Enforcement Administration; established to enforce the Controlled Substance Act. |
FDA | Food and Drug Administration; inspects drug facilities, receives new drug applications, investigates and removes harmful drugs, requires proper labeling; developed the classification system related to medication effects on unborn fetuses. |
The Joint Commission | nonprofit organization that evaluates and accredits health care organizations and programs. |
OTC | non-prescribed medications; Over the Counter medications. |
PDR | Physician's Desk Reference; the most frequently used pharmacology resource. |
USP-NF | United States Pharmacopeia and National Formulalry; the official medication list recognized by U.S. government. |