Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.

Remove Ads
Don't know
remaining cards
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards

Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Lysosomal Diseases

MGM Exam 2

Hurler syndrome enzyme: alpha-L-iduronidase accumulation of HS and DS symptoms: MR, dystosis multiplex, corneal clouding (LSD I)
Hunter syndrome enzyme: iduronate sulfatase accumulation of HS and DS symptoms: mild LSD I without corneal clouding X-LINKED!!!! (LSD II)
Sanfillipo Syndrome A enzyme: heparan N-sulfamidase accumulation of HS symtoms: severe CNS (LSD IIIa)
Sanfillipo Syndrome B enzyme: N-acetyl-alpha-D-glucosaminidase accumulation of HS symptoms: severe CNS effects (GSD IIIb)
Morquio Syndrome enzyme: hexosamine-6-sulfatase accumulation of KS symptoms: bone changes and cloudy cornea, does not affect intelligence (LSD IV)
Maroteaux-Lamy Syndrome enzyme: arylsufatase B accumulation of DS symptoms: severe bone and soft tissue change with corneal change (LSD VI)
Mucolipidosis (LSD VII) enzyme: beta-glucouronidase accumulation of HS and DS symptoms: hepatosplenomegaly and dysostosis multiplex
I-cell disease inability to phosphorylate mannose, can't get lysosomal enzymes into lysosomes; dysostosis multiplex
Created by: insanejuliafan