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T2DM

DM Drug MOA

QuestionAnswer
Alpha-Glucosidase Inhibitors Delay digestion of carbohydrates
Amalyin Analog Prolongs gastric emptying, Reduces postprandial glucagon secretion, Suppresses appetite
Biguanide Decreases hepatic glucose production, Decreases intestinal absorption of glucose, Improves insulin sensitivity
DPP-IV Inhibitors inhibits DPP-IV which breaks down GLP-1, therefore increasing insulin secretion and suppressing glucagon secretion
GLP-1 Agonists increases insulin secretion and suppresses glucagon secretion through mimicking the effects of GLP-1
Meglitinides stimulate the release of insulin from the pancreas
SGLT-2 Inhibitors increases renal excretion of glucose by preventing reabsorption in the kidneys, also increases the amount of glucose filtered by the kidneys
Sulfonylureas increases the secretion of insulin by the pancreas
TZDs increase target cell insulin sensitivity through ppar gamma agonism
Created by: kornblum