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Skin System
WVSOM: Skin System (Sammon's Lectures)
| Question | Answer |
|---|---|
| Organism for hottub folliculitis | psuedomonas |
| Acne vulgaris is an dlock of what | pilsebaceous unit |
| Neonatal acne is caused by what | left over hormones from mother |
| Whats different about acne rosacea | NO comedones |
| What is different between inflammatory and non-inflammatory | Inflammatory has a IMMUNE response, redness and papules/pustles/nodules |
| What does Benzy peroxide do | reduces number of P. Ance |
| What do antibiotics do for ance | reduce inflammation |
| Only acne drug to ever be shown to reduce effectivness of birth control | rifampin |
| Caused by pox virus and has pink umbilicated papules | Molluscum Contagiosum |
| Itches most at night | scabies |
| What causes the itching in scabies | scobala, or the poop |
| A individual with Karposi's sarcoma should be tested for... | HIV |
| Is a wheal a primary or secondary lesion | primary |
| Is a tumor a primary or secondary papule | primary |
| Do erosions or ulcers heal w/o scarring | erosions |
| What is an excoriation | erosion caused by scratching |
| A thickened epidermis caused by scratching is called a.... | Lichenification |
| Will hypopigmentation or depigmentation light up under a Woods lamp | DEpigmentation |
| Which two types of cleansers have the highest (basic) pH | soaps and combars |
| Which type of cleanser should you use on infants | syndets |
| True or False: Moisterizers put water back into the skin | FALSE, just keep water in |
| Most effective occlusive moisturizer | petrolatum |
| What do humectants do? | Pull water from enviornment (requires humidity above 70%, cause Keratinocytes to swell) |
| Which skin products are used in between washing and moisturizing | astrigents and toners |
| Two mechansims behind sunscreen? Which one is poor for controlling UVA? | block/absorb the UV energy and reflect it.UVA. |
| At which SPF do you get both UVA and UVB protection | 30 |
| Which UV source, A B or C, is more erythrogenic and seasonal | UVB |
| What is the proper order of ability to keep in moisture between creams, oinments and lotions | ointment > creams > lotions |
| Is it a good idea to use combinations of steroids and antibiotics? | NO |
| What is tachyphylaxis | reduced response to a drug due to enzyme induction and thus normal durg dose becomes ineffective |
| 'Cidal' drugs work to reduce fungi by what mechanism | killing them |
| 'Static' drugs work to reduce fungi by what mechansim | supressing them |
| Waxy brown "stuck on" plaques that look like they coudl just peel off are indicative of... | Seborrhetic keratosis |
| Skin tags occur in areas of... | Friction (DO NOT remove with string, more common in the obese, LOTS of bleeding when removed) |
| Usually found on the lower legs, these are TOUGH to the touch, and havea POSITIVE DIMPLE SIGN | Dermatofibroma |
| Pruigo Nodularis is what? Commonly linked to? | Itching nodular disease linked to psych disorders |
| Hyperpigmentation, usually on the face and seen 10x as much in women | Melasma |
| 6 or more cafe au lait spots can lead you to think about... | von Recklinghous disease |
| Congeital small bumps on the buttocks, back of legs, and anterior legs | Keratosis Pylaris |
| Vititigo is caused by what | actual autoimmune disease that attacks melanocytes |
| Cough, coryza and conjunctivitis | Measles |
| A disease that manifests a rash as soon as a high fever breaks | rosiola |
| Caused by coxsackie virus | Hand-foot-mouth disease |
| Alopecia Atreata is caused by.. | autoimmune disease against the pigment in the hair follicles |
| True or False: The presence of auto-reactive antibodies are enough to warrent a diagonsis of some kind of disease (lupus, etc...) | False |
| Strongest risk factor for Lupus | Gender (females at more risk) |
| At what age does Lupus most often occur | childhood |
| In which ethnicities does Lupus most often occur | African Americans |
| 'MD SOAP BRAIN' is used to describe what? What does it stand for | Systemic Lupus. Malar Rash, Discoid lesiosn, Arthritis, Photosensitivity, Photosensitivity, Blood disorder, ANA, Immune response, Nueropathy |
| How many traits out of the 11 diagnotic criteria does a patient need to have in order to be diagnosed as having systemic lupus | 4 |
| In which form of lupus is ANA NOT expected to be seen | Discoid Lupus |
| In which type of Lupus woudl you seen "carpet-tac lesions" | Discoid |
| SS-A and SS-B antibodies | Subacute Lupus |
| Papulosquamous and Annular Polycyclic pattern | Subacute Lupus |
| What disease 'spares the knuckles' | Subacute lupus |
| Which Lupus is ANA positive and has Anti-histone antibodies | Drug induced antibodies |
| Which drug has been highly associated with drug induced lupus | menecillin |
| SS-A negative with possible SS-B positive or neagtive | Neonatal lupus |
| which lupus is associated with congenital heart block | neonatal lupus |
| Dermatomyositis is actually inflammation in which tissue that presents cutaneously | muscle |
| A case of dermatomyositis shoudl lead you to suspect... | Ovarian cancer in females |
| While Lupus tends to spare the knuckle, which disease will manifest right on top of them | dermatomyositis |
| A positive anti-Jo-1 antibody | Dermatomyositis |
| CREST syndrome satnds for what and is assocaited with which disease | Calcinosis Cutis, Raynaud Phenomenon, Esophageal dysmotility, Sclerodacytly, Teleangecasia and is associated with Systemic Sclerosis |
| Whar is the localized form of sclerodoma called | Morphia |
| Autoantibodies to Type II Collagen | Relapsing Polychondritis |
| ant-U1-RNP antibodies | Mixe connective tissue disease |
| WHich has a higher malignancy, congeital or acquried Nevi | congenital |
| The tyndal effect is what | Brown pigments that absorb longer wavelengths of light apparently turning them blue |
| What type of Nevi has a "fried egg" appearance | Dysplastic Nevi |
| What is a Beckers Nevi | NOT a true melanocytic nevi. Overgrowth of smooth muscle seen on SHOULDER. Also is usally seen on a brown papule and has hair |
| An immune reaction toward a Nevi may yeild what type of Nevi | Halo Nevi |
| What are the two most common forms of malignant melanomas | Spreading (70%) and nudular |
| This is a malignant melanoma effecting mostly african americans and asians and occurs on the soles, phalanges, palms and mucous membrane | Lentigo Maligna |
| A pigmented band that occurs in a nail or nail fold | Hutichinsons Sign |
| ABCDE's of melanomas stand for... | Asymetry, borders, color, Diameter and Evolving |
| At which Breslow depth do you sample the sentinal lymph node | 1mm |
| What was psoriasis thought to be linked to | Leprosy |
| Well demarcated, erthematous plaques, with scales | psoriasis |
| What pathological mechanism is thought to be associated with psoriasis | T-cell disease |
| Urethritis, arthritis and psoriasis altogether makes up which disease | Reiters |
| Methotrexate is damaging to what organ | Liver |
| Cyclosproin is damaging to what organ | Kidney |
| Guttate psoriais is linked to what bacterial infection | strep |
| Erythema multiform is linked to which type of infection | herpes |
| Erythema NOdosum is most commonly caused by.. | oral birth control or coccidiovirus in San Jaun Valley |
| Very common and is seen as Cradle Cap in newborns. Has a greasy scale and minor itching | Seborrehtic dermatitis |
| Red-orange plaques, follicular papules and Islands of Sparing | Pityriasis Rubra Pilaris |
| Christmas tree pattern, Herald Patch, Collarette scale and Syphilis | Pityriasis Rosea |
| Pruitic, Planar, Polyangular, purple, papules | Lichen Planus |
| Where will lichen planus ALWAYS manifestq | buccal mucosa |
| Lichen sclerosis is treated with what | CLASS 1 STEROIDS |
| Gumma are seen when | stage 3 syphilis |
| Copper colored oval papules are seen with moth eatch alopecia in which disease | syphilis, stage 2 |
| Gluten sensitive enteropathy | Dermatitis Herpetiformis |
| Which disease has IgA deposited associated with GI hemorrage and abnormal jejunal mucosa | Dermatitis Hepretiformis |
| anti-desmoglein 1 and 3 antibodies | pemphigus |
| BP230 and BP180 antibodies | Pemphigoid |
| Four phases of wound healing | INflammatory, Migratory, Proliferative, and Late-proliferative |
| Erythema, edema, heat and pain occur in which stgae of healing | inflammatory |
| Angiogenesis occurs in which stage of healing | migratory |
| Fibroblast and conraction dominate which stage of healing | proliferative |
| Most dog bites are treated with which wound intention | primary |
| Snake bites are usually treated with which intention | secondary |
| Human bites are treated with which intention | tertiary |
| Which vitamin is MOST important in healing | vit C |
| Which trace element is most important in healing | Zinc |
| Do steroids help wound healing | NO |
| Do anti-inflammatories inhibit wound healing | NO |
| Besides steroids, which condition is extremely detrimental to wound healing | diabetes |
| Does ionizing radiation have more effects on basal cell or squamous cell carcinoma | niether! |
| Smoking, Arsenic and HPV increase risk for | SCC |
| Bowens disease is associated with what | Squamous cell in situ |
| Pearly Papule with plaque or depressed center | BCC |
| What is the treatment of choice for Morpheaform BCC | Mohs |
| What are the levels of toxicity for lidociane with and w/o epi | 7mg WITH eip, 5mg w/o |
| Do you use punch biposies on a malignant tumor | no |
| Which causes more damage electrodessication or electrofulgaration | electrodesication |
| Diuretic that you DO NOT want to give during pregnancy | Spironalactone |
| Palpable Purpura are associated with... | vasculitis |
| Pityriasis Rosea is associated with which viral infection | syphylis |
| Lichen Planis is associated with which viral infection | Hep c |
| Are you able to remove a mephiaform BCC in the office | NO |