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Renal Phsy

renal physiology

60% of this substance is filtered and 90% reabsorbed by the proximal tubule and thick ascending limb Calcium
Loop diuretics increase its urinary excretion and PTHand thiazides increases it's reabsorption Calcium
85% is reabsorbed in the proximal tubule by sodium phophate cotransport phosphate
PTH inhibits it's reabsorptiona dn it is a urinary buffer Phospate
50% is reabsorbed passively in the proximal tubule and ADH increases permeability of collecting ducts to it Urea
Factors that change the distal reabsorption of potassium dietary intake, Aldosterone( increases secretion), Acid-base(acidosis decreases secretion, Alkalosis increases), thiazides and loop diuretics( increase secretion), and K sparing agents
Filtration occurs freely and the proximal tubules reabsorb 67% with sodium and water, loop og henle reabsorbes 29% by sodium-potassium-2chloride cotransporgt potassium
in the distal tubules I cells reabsorb with h-k-ATPase and occurs on a low K diet, while secretion occurs in P cells bu na-k pump potassium
Early distal-reabsorbes by Na-Cl cotransport and because of thiazides Sodium
P-cells reabsorb na/h2o and secrete potassium, Aldosterone increases sodium reabsorption and potassium secretion sodium
25 % is reabsorbed in the ascending loop by Na-K-2Cl cotransport sodium
proximal tubule reabsorbs 2/3 , is reabsorbed with glucose, amino acids, phophate, lactate and counter transportedwith H+ sodium
Filtration fraction the fraction of fenal plasma flow filtered across glomerular capillaries, equals.20, = GFR/RPF
( urine concentration X urine flow)/plasma flow GFR
accomplishe dby changing renal vascular resistance though myogenic and tubuloglomerular feedback autoregulation of RBF
indicates volume of plasma that is cleared of a substance per unit time, ( urine concentration X urine volume)/ plasma concentration clearance equation
25% of cardiac output, = (RPF)/ 1-Hct renal blood flow
vasoconstriction caused by sympathetic nervous system and angiotensin II, increases GFR decreased RBF
vasodilation caused by prostaglandins, dopamine increased RBF
Created by: swohlers