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Renal Phsy
renal physiology
| Question | Answer |
|---|---|
| 60% of this substance is filtered and 90% reabsorbed by the proximal tubule and thick ascending limb | Calcium |
| Loop diuretics increase its urinary excretion and PTHand thiazides increases it's reabsorption | Calcium |
| 85% is reabsorbed in the proximal tubule by sodium phophate cotransport | phosphate |
| PTH inhibits it's reabsorptiona dn it is a urinary buffer | Phospate |
| 50% is reabsorbed passively in the proximal tubule and ADH increases permeability of collecting ducts to it | Urea |
| Factors that change the distal reabsorption of potassium | dietary intake, Aldosterone( increases secretion), Acid-base(acidosis decreases secretion, Alkalosis increases), thiazides and loop diuretics( increase secretion), and K sparing agents |
| Filtration occurs freely and the proximal tubules reabsorb 67% with sodium and water, loop og henle reabsorbes 29% by sodium-potassium-2chloride cotransporgt | potassium |
| in the distal tubules I cells reabsorb with h-k-ATPase and occurs on a low K diet, while secretion occurs in P cells bu na-k pump | potassium |
| Early distal-reabsorbes by Na-Cl cotransport and because of thiazides | Sodium |
| P-cells reabsorb na/h2o and secrete potassium, Aldosterone increases sodium reabsorption and potassium secretion | sodium |
| 25 % is reabsorbed in the ascending loop by Na-K-2Cl cotransport | sodium |
| proximal tubule reabsorbs 2/3 , is reabsorbed with glucose, amino acids, phophate, lactate and counter transportedwith H+ | sodium |
| Filtration fraction | the fraction of fenal plasma flow filtered across glomerular capillaries, equals.20, = GFR/RPF |
| ( urine concentration X urine flow)/plasma flow | GFR |
| accomplishe dby changing renal vascular resistance though myogenic and tubuloglomerular feedback | autoregulation of RBF |
| indicates volume of plasma that is cleared of a substance per unit time, ( urine concentration X urine volume)/ plasma concentration | clearance equation |
| 25% of cardiac output, = (RPF)/ 1-Hct | renal blood flow |
| vasoconstriction caused by sympathetic nervous system and angiotensin II, increases GFR | decreased RBF |
| vasodilation caused by prostaglandins, dopamine | increased RBF |
Created by:
swohlers
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