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BK1
Ben Kean lecture 1
| Question | Answer |
|---|---|
| What is a trophozoite? | A motile stage that normally reproduces asexually |
| What is a cyst? | A non-motile more resistant stage |
| What is a sporozoite? | An infective stage produced in a oocyte |
| What are the principle malaria species? | Plasmodium, Falciparum, Vivax and Malaria |
| Where do the malaria sporozoites go 1st? | They go to liver and reproduce via asexual reproduction called schizogeny |
| What is the liver malrai stage alled? | It is asymptomatic and results in daughter protozoa called merozoites |
| Where do the merozoites in liver go after they are ruptured? | They invade the RBCs and asexually reproduce |
| What is malria stained with? | Giemsa, Wrights and Romankasky dyes |
| What color is the cytoplams and nucleus of malaira | Cyto-blue nucleus red |
| What fruit does malaria look like in thick and thin film? | Banana |
| What kind of fever does falciparum have? | Contiunous, irregular spikes |
| What kind of fever does vivax have? | 48 hrs, tertian malaria |
| What kind of fever does ovale have? | 48 hrs, tertian |
| What kind of fever does malariae have? | Quarten |
| What are the most common symptoms of malaria? | Fevers and chills, headaches, myalgias, nausea, vomitting, diarrhea, abdominal pain, weight loss, malaria fever |
| What cause the most severe malaria? | P. Falciparum |
| How does the shape of p.vivax differ from p.falciparum? | vivax has more of an amoiboid shape |
| What are teh schuffners dots related to? | These are small dots in the cytoplasm |
| Why does P vivax require primaquine for treatment? | It establishes hypnozoites in the liver |
| Which is the malaria outside of africa? | P. Ovale |
| Who are most susceptible to toxo? | Pregnant women and immuno |
| How do you get get toxo? | Ingestion of bradyzoites in infected meat, from oocyte contaminated unwashed vegetables or pussy cats |
| Are toxoplasma ooctyes immediately infecious? | No |
| Whats the risk for maternal fetal transmission in toxo? | 25% in 1st trimester, 65% in 3rd |
| What severe fetal disease may the baby get in toxo? | Hydrocephales, mental retardation, erebral calcifications |
| How do you look for toxo? | brain |
| What are teh ways to diagnose toxo? | 1)Serological 2)Direct identification of blood 3)PBS |
| What are teh clinical manifestations? | 1)Asymptomatic adenopathy 2)Mono like 3)Chorioretinitis 4)Encephalitis 5)Myocarditis 6)PCP like |
| At what CD4 count do you see PCP? | <200 |
| What are teh classic findings of PCP? | Nonproductive cough, dyspnea, fever |
| What does PCP look like on CXR? | Diffuse bilateral |
| Do you use thick or thin film? | Thick for yes/no, thin for diagnosing. |
Created by:
villagejoker
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