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Chapter 11

Vocab Review

agonists Drugs that activate receptors to accelerate or slow normal cellular function.
antagonists Drugs that bind with receptors but don't activate them. They block receptor action by preventing other drugs or substances from activating with them.
receptor The cellular material located at the site of the action that interacts with the drug.
site of action The location where an administered drug produces an effect.
hydrophilic Capable of associating w/ or absorbing water.
hydrophobic Water repelling; can't associate with water.
half-life Amount of time it takes for the blood concentration of a drug to decline to one-half of an initial value.
absorption The movement of a drug from the dosage formulation into the blood.
bioavailability The amount of an administered dose that reaches the general circulation and the rate at which this occurs.
bioequivalency The comparison of bioavailability b/w two dosage forms.
pharmaceutical equivalent Drug products that contain identical amounts of the same active ingredient in the same dosage form.
therapeutic equivalent Pharmaceutical equivalents that produce the same effects in patients.
Orange Book Provides info on the therapeutic equivalence of brand and generic drugs.
Created by: Ms.little1