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Chaney 2 - Exam2

Lipids

QuestionAnswer
Lauric 12:0 medium-chain fatty acids absorbed directly into bloodstream found in palm & coconut oil raise serum cholesterol levels
Myristic 14:0
Palmitic 16:0 saturated fatty acid found in meats & dairy raises serum cholesterol levels
Stearic 18:0 saturated fatty acid also found in meats neutral or cholesterol lowering effect
Oleic 18:1 omega 9 monounsaturated fatty acid found in olive & peanut oils lowers cholesterol without lowering HDL part of “Mediteranian Diet”
Linoleic 18:2 omega 6 essential polyunsaturated fatty acid an w6 fatty acid found in vegetable oils lowers serum cholesterol
Linolenic 18:3 omega 3 essential polyunsaturated fatty acid an w3 fatty acid also found in vegetable oils lowers serum cholesterol
Arachidonic 20:4 omega 6 w6 polyunsaturated fatty acid made from linoleic acid precursor to w6 eicosanoids
Eicosopentanoic (EPA) 20:5 omega 3 w3 polyunsaturated fatty acids made from linolenic acid (inefficiently) found in cold water fish & canola oil precursors to w3 eicosanoids may decrease heart disease risk (see CC) anti-inflammatory DHA important for early
Docosahexanoic (DHA) 22:6 omega 3 w3 polyunsaturated fatty acids made from linolenic acid (inefficiently) found in cold water fish & canola oil precursors to w3 eicosanoids may decrease heart disease risk (see CC) anti-inflammatory DHA important for early
Apo A activates LCAT involved in HDL binding to tissues
Apo C activates lipoprotein lipase
Apo E involved in binding of chylomicron and VLDL remnants and HDL to the liver AFTER removal of most TG
Apo B100 involved in LDL binding to LDL receptor, also works with apo E in binding of IDL to LDL receptors
apos for Chylomicron B48, E, A, C
apos for VLDL B100, E, C
apos for LDL B100
apos for HDL A, C, E
lipoprotein lipase in adipose + striated muscle, hydrolyzes TG and PL from chylomicrons and large VLDL insulin increase activity
hepatic lipase Liver, hydrolyzes TG and PL of small VLDL, IDL, and large HDL insulin independant activity
Lecithin-cholesterol acyltransferase (LCAT) Liver, esterifies cholesterol in HDL
Cholesterol ester transfer protein (CEPT) liver, spleen, adipose, and intestine, transfers CE from HDL to VLDL and LDL
chylomicron and VLDL very low density lipoproteins w/ high concentrations of TG in core
LDL and HDL more dense lipoproteins, high concentration of CE in core
Created by: MouserKat