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Chaney 2 - Exam2
Lipids
Question | Answer |
---|---|
Lauric | 12:0 medium-chain fatty acids absorbed directly into bloodstream found in palm & coconut oil raise serum cholesterol levels |
Myristic | 14:0 |
Palmitic | 16:0 saturated fatty acid found in meats & dairy raises serum cholesterol levels |
Stearic | 18:0 saturated fatty acid also found in meats neutral or cholesterol lowering effect |
Oleic | 18:1 omega 9 monounsaturated fatty acid found in olive & peanut oils lowers cholesterol without lowering HDL part of “Mediteranian Diet” |
Linoleic | 18:2 omega 6 essential polyunsaturated fatty acid an w6 fatty acid found in vegetable oils lowers serum cholesterol |
Linolenic | 18:3 omega 3 essential polyunsaturated fatty acid an w3 fatty acid also found in vegetable oils lowers serum cholesterol |
Arachidonic | 20:4 omega 6 w6 polyunsaturated fatty acid made from linoleic acid precursor to w6 eicosanoids |
Eicosopentanoic (EPA) | 20:5 omega 3 w3 polyunsaturated fatty acids made from linolenic acid (inefficiently) found in cold water fish & canola oil precursors to w3 eicosanoids may decrease heart disease risk (see CC) anti-inflammatory DHA important for early |
Docosahexanoic (DHA) | 22:6 omega 3 w3 polyunsaturated fatty acids made from linolenic acid (inefficiently) found in cold water fish & canola oil precursors to w3 eicosanoids may decrease heart disease risk (see CC) anti-inflammatory DHA important for early |
Apo A | activates LCAT involved in HDL binding to tissues |
Apo C | activates lipoprotein lipase |
Apo E | involved in binding of chylomicron and VLDL remnants and HDL to the liver AFTER removal of most TG |
Apo B100 | involved in LDL binding to LDL receptor, also works with apo E in binding of IDL to LDL receptors |
apos for Chylomicron | B48, E, A, C |
apos for VLDL | B100, E, C |
apos for LDL | B100 |
apos for HDL | A, C, E |
lipoprotein lipase | in adipose + striated muscle, hydrolyzes TG and PL from chylomicrons and large VLDL insulin increase activity |
hepatic lipase | Liver, hydrolyzes TG and PL of small VLDL, IDL, and large HDL insulin independant activity |
Lecithin-cholesterol acyltransferase (LCAT) | Liver, esterifies cholesterol in HDL |
Cholesterol ester transfer protein (CEPT) | liver, spleen, adipose, and intestine, transfers CE from HDL to VLDL and LDL |
chylomicron and VLDL | very low density lipoproteins w/ high concentrations of TG in core |
LDL and HDL | more dense lipoproteins, high concentration of CE in core |