Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Don't know
remaining cards
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Cards Lipid Mgmt


Lipid screening: there is relationship between Total Chol & LDL and: Risk of CHD & coronary mortality
Lowering LDL in moderate / high risk patient leads to: Fewer CV events
Mgmt of Low HDL-C Wt reduction & increased physical activity; LDL-C is primary target of tx; Non-HDL-C is secondary target of tx (if trigs >200 mg/dL); consider nicotinic acid or fibrates
ATPIII chol screening for pt w/o CHD: LDL < 160 & 0-01 risk factor; or LDL <130 & >1 risk factor: rescreen in 5 yrs
ATPIII risk determination Step 1 1. Fasting lipid level
ATPIII risk determination Step 2 2. determine CHD equivalents
ATPIII risk determination Step 3 3. Major CHD factors other than LDL
ATPIII risk determination Step 4 4. If >1 non-LDL CHD factor (in pt w/o CHD or equivalent): use modified Framingham criteria
ATPIII risk determination Step 5 5. Detn risk category to establish LDL goal, when to initiate tx lifestyle changes, & when to consider drug tx
ATP III criteria: Metabolic syndrome Dx criteria 3 of 5: central obesity (waist men >40 in & women >35); trigs ≥150; HDL <40 (M) & <50 (F); BP ≥130/85; FPG ≥100 or Dx of DM
IDF metab syndrome definition Increased waist girth + any 2: Trigs >150; HDL <40 (M) & <50 (F); SBP >130, DBP >85, or HTN tx; FPG >100 or prior dx type 2 DM
CV risk factors in DM pts Type I: high trigs & HTN. Type 2: dyslipid, HTN, ins resistance, obesity, FH atherosclerosis; SMK NOT risk factor for I or 2
3 levels of prevention Primary: remove risk factors; secondary: early detection & tx; tertiary: reduce complications
A) fats that contribute to CV disease; B) fats that may be cardioprotective A. Saturated & trans fat. B. monounsaturated & polyunsaturated fat
Framingham: MI risk MI risk increases by 25 percent for every 5 mg/dL decrement in HDL below median values
Low HDL: risk factors SMK; sedentary;obese; insulin resistant/ DM; hypertriglyceridemia; chronic inflammatory dz
Cardioprotective HDL levels = >60 mg/dL (>75 assoc w/ longevity syndrome)
ATP III: normal triglyceride level = <150
ATP III: borderline high triglyceride level = 150-199
ATP III: high triglyceride level = 200-499
ATP III: very high triglyceride level = >500
Primary concern w/ ATPIII borderline high TGs: Metabolic syndrome
Primary concern w/ ATPIII High category CHD
Primary concern w/ ATPIII Very High category pancreatitis
ATP III recommends Chol screening how often? at least every 5 yrs for pts 20 or older
Pts w/ borderline-high chol & <2 risk factors should be rescreened: within 1-2 yrs
Framingham risk factors Age, TC, HDL, BP, & SMK
HLD: eye sxs xanthelasmas (sharply demarcated yellowish fat deposits around eyelids; arcus senilis; lipemia retinalis (if TG >2000)
4 primary RFs for atherosclerosis Smoking, hypertension, diabetes mellitus, hypercholesterolemia
ATP III: Hypertriglyceridemia >150 mg/dl
ATP III: Low HDL Cholesterol <40 mg/dl
ATP III: Optimal LDL = <100 mg/dl
ATP III: High LDL = >160 mg/dl
ATP III: Goal LDL for pts with 2 Risk Factors = <130 mg/dl (<160 for 1 RF)
ATP III: Goal LDL in high risk populations (CAD, DM) <100
Goal LDL in VERY high risk pts (10-yr risk of cardiac event 20%, recent MI, CAD+DM, CAD+smoking, CAD+metabolic syndrome) = <70
CAD RFs Smoking, HTN, low HDL (<40), FH early CHD (1st degree M<55 or F<65), Age (M>45, F>55)
ATP III: Desirable Total Cholesterol = <200
ATP III: Borderline High Total Cholesterol = 200-239
ATP III: High Total Cholesterol = >240
1stline tx for high triglycerides Fibrates (gemfibrozil / Lopid) [AE: rhabdo]
2ndline tx for high triglycerides Niacin (nicotinic acid): decreases serum apolipoprotein B-100; AE: flushing. Omega-3 fatty acids
Tx for Dyslipidemia / high LDL 1stline: lifestyle modifications. 2nd: statins (HMG-CoA reductase inhibitors)
Bile acid sequestrants: MOA Work in the GI tract (not systemically absorbed); inhibit emulsification of triglycerides. Cholestyramine (Questran), colestipol, colesevelam
Consistent predictor of DM, CHD, and mortality = Waist circumference (>TG, Chol, wt)
Metabolic syndrome is most prevalent in which ethnic group? Mexican American
One of the most sensitive predictors of CAD is this lab value = TC : HDL ratio
Niacin is associated with a reduction in: CAD
A primary dietary source of omega-6 FAs is: Flax seed
Primary concern (AE) in use of fibrates and statins is the potential for: Rhabdomyolysis
In a 54 yo male with metabolic syndrome, CAD, & current hx of smoking, what is the LDL goal? <70
In a 56 yo female with current hx of smoking, what is the LDL goal? <130
In a 42 yo male with no CAD risk factors, what is the LDL goal? <160
Created by: Abarnard