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RS Microbiology
Respiratory System Microbiology - Bacteriology-Atypical Pneumonia
| Question | Answer |
|---|---|
| Atypical pneumonia is caused by: | Mycoplasma-Chlamydia-Legionella Gram -ve bacteria Few LPS |
| Symptoms of atypical pneumonia: | Dry cough & mild fever often persist for weeks |
| What is the smallest known bacteria? | M. pneumonia |
| Cell wall of M. pneumonia: | Lack true cell wall |
| Mycoplasma pneumoniae causes | Cause serious respiratory disease and death |
| How is M. pneumoniae spread? | Droplet infections |
| Symptoms of M. pneumonia: | Low fever & dry cough symptoms Eventually, Mild rashes, neurological syndromes Acute/ Subacute Pharyngitis & Bronchitis -children, young adults |
| Lab diagnosis of M. pneumoniae: | Special culture medium Mycoplasma specific DNA by PCR Sputum,Pleural fluid,Blood Serological Cold-Agglutination Test: Increased Ab titers after 4-weeks |
| Treatment of M. pneumoniae: | Levofloxacin, moxifloxacin, Macrolides/ Azithromycin NO vaccine |
| Characteristics of Chlamydia: | Obligate intracellular bacteria causing intracytoplasmic inclusions Rapidly killed outside body tissues, Dryness & high temperature |
| Life cycle of Chlamydia: | Infectious elementary bodies attached to lung mucosa and promoting its entry into lung tissues Reticulate bodies developed as inclusion bodies in cytoplasm phagosomes & released new Infectious elementary bodies |
| Chlamydia trachomatis is a common cause of: | Sexually transmitted disease (STD) Nonspecific urethritis Transmitted from mother to newborn babies Severe pneumonia Eye infection Conjunctivitis & Trachoma |
| Chlamydia pneumonia is related only to; | The respiratory tract |
| C. Pneumonia is transmitted by: | Resp. droplets |
| Symptoms of C. pneumonia: | Mild respiratory symptoms, dry irritating prolonged cough, nasal congestion with/without fever No blood sepsis Infection in adults often asymptomatic, mild, may include sore throat, headache, fever, dry cough. Rare Acute infection |
| Diagnosis of C. pneumonia: | Sputum, throat-nasal swabs, MaCoy Cell Culture, ELISA Specific antibodies, PCR |
| Treatment of C. pneumonia by: | Macrolides, Tetracyclines, levofloxacin, moxifloxacin NO Vaccine |
| Characteristics of Legionella: | Flagella Widely spread in cold natural water bodies and wet soil Facultative Anaerobes Grow in Cold/Hot water(0- 80C) Transmitted by inhalation of contaminated water drops Cause single cases /more outbreak of disease |
| Incubation period of Legionella: | 2-10 days |
| Symptoms of Legionella: | High fever Nonproductive dry cough Mild fever at start Blood sepsis Shortness of breath Chest & Muscles pain Joint pain Diarrhea Renal failure |
| Risk factors of L. pneumonia: | Heavy cigarette smoking Old age Underlying diseases such as renal disease, cancer, diabetes, chronic pulmonary obstructions, suppressed immune systems Corticosteroid therapy High death rate in patients with presence lung obstructions |
| Diagnosis of L. pneumonia: | Special culture media.. blood/urine specimen for detection Specific antibodies or Antigens by PCR, or ELlSA |
| Treatment of L. pneumonia: | Macrolides/azithromycin, levofloxacin, moxifloxacin NO Vaccine |
Created by:
Ulaisl
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