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DM Medications
Common Diabetic Medications
| Question | Answer |
|---|---|
| Which class of medications decreases hepatic glucose production? | Biguanides |
| What are the two classes of insulin secretagogues? | Sulfonylureas, Glinides (Meglitinides) |
| Which is the less-potent insulin secretagogue? | Glindides (Meglitinides) |
| What is the main risk with insulin secretagogues? | Hypoglycemia |
| What are the two brand names of Sulfonylureas (insulin secretagogues) | Amaryl, Glucotrol |
| What are the two brand names of Glinides (insulin secretagogues | Prandin, Starlix |
| What is the treatment for hypoglycemia? | Rule of 15's: 15 g fast-acting CHO Wait 15 min Check BG If <70, repeat If no meal is planned, test within 60 minutes again |
| What foods are equivalent to 15 g of fast-acting CHO to treat hypoglycemia? | 3 glucose tablets 1/2 c fruit juice 6 Saltines 1T honey or syrup 5 Lifesavers |
| What is the name of the class of Insulin Sensitizer drugs? | Thiazoladinediones, Biguanides |
| What drugs increases insulin sensitivity at the muscle and liver? | Thiazoladinediones, Biguanides |
| What are the main side effects of insulin sensitizers? | Nausea, loss of appetite |
| What are the main side effects of Thiazoladinediones? | Nausea, loss of appetite |
| What are the main side effects of Biguanides? | Nausea, loss of appetite |
| Under what class of drug is Glucotrol? | Sulfonylurea |
| Under what class of drug is Amaryl? | Sulfonylurea |
| What do Sulfonylureas do? | Cause the pancreas to secrete insulin |
| What does Glucotrol do? | Cause the pancreas to secrete insulin |
| What does Amaryl do? | Cause the pancreas to secrete insulin |
| What do Glinides/Meglitinides do? | Cause the pancreas to secrete insulin |
| What does Prandin do? | Cause the pancreas to secrete insulin |
| What does Starlix do? | Cause the pancreas to secrete insulin |
| What are the brand names of Thiazoladinediones | Actos, Avandia |
| What does Actos do? | Increases insulin sensitivity at muscle and liver |
| What does Avandia do? | Increases insulin sensitivity at muscle and liver |
| Under what class of drugs is Actos? | Thiazoloadinediones |
| Under what class of drugs is Avandia? | Thiazoladinediones |
| What do biguanides do? | Prevent the production of glucose in the liver, improve the body's sensitivity towards insulin and reduce the amount of sugar absorbed by the intestines |
| What are the brand names of biguanides? | Metformin, Glucophage |
| Under what class of drug is Metformin? | Biguanide |
| Under what class of drug is Glucophage? | Biguanide |
| What do alpha-glucosidase inhibitors do? | Affect gut enzymes that diges CHO to slow CHO absorption; keeps BG lower |
| What drugs slow CHO absorption? | Alpha-glucosidase inhibitors |
| What drugs can cause diarrhea and gas? | Alpha-glucosidase inhibitors |
| What are the types of Alpha-glucosidase inhibitors? | Acarbose, Miglitol |
| What is the brand name for Acarbose and what class is it under? | Precose, Alpha-glucosidase inhibitors |
| What is the brand name for Miglitol and what class is it under? | Glyset, Alpha-glucosidase inhibitors |
| What class of drugs can help with weight control? | Alpha-glucosidase inhibitors |
| What do DPP4 inhibitors do? | Send a message to Dpp4 (gut hormone). DPP4 signals pancreas to make insulin what BG is increased and signals the liver to make less glucose |
| What does DPP4 do? | Signals pancreas to make insulin what BG is increased and signals the liver to make less glucose |
| What is the brand name for Sitagliptin? | Januvia (DPP4 Inhibitor) |
| What is the other name for Januvia? | Sitagliptin (DPP4 inhibitor) |