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FSHN 450-3 Trsplants
Question | Answer |
---|---|
Autologous | bone marrow or stem cells from host |
Allogenic | bone marrow/stem cells or organ from donor |
Xenogenic | organ from different species (ethical/rejection issues) |
Humoral response | antibodies |
Cell-mediated response | T-cells |
5 mechanisms of anti-rejection drugs | purine synthesis, inhibit cytokine production, inhibit binding, inhibit T-cell activation, suppress T-cell maturation or proliferation |
organ matching | blood type, antibodies, MHC |
what juice to avoid with immunosuppressive drugs? | grapefruit |
cardiac cachexia | hypermetabolic, congestion/edema, eating increases O2 req |
LVAD | left ventricular assist device (increases QOL when waiting for heart/lung transplant) |
Primary biliary cirrhosis | immune system attacks bile ducts |
Sclerosing cholangitis | scarring and narrowing of bile ducts inside and outside of liver |
Biliary atresia | malformation of the bile ducts |
Wilson’s disease | abnormal levels of copper in liver |
Hemochromatosis | accumulation of iron in liver |
Vascular anastomosis | connecting vasculature during transplants |
Protein kidney/liver vs. others | less to not ruin new organs |