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DU PA Syn Flu Analy
Duke PA Synovial Fluid Analysis
Question | Answer |
---|---|
general marker of inflammation | ESR |
most commonly assessed acute phase reactants as markers of inflammation | ESR, CRP |
sed rate | ESR |
use a __ top tube for sed rate | lavender |
rate at which RBC's fall to bottom of anticoagulated column in a specific time period | ESR |
ESR is | not sensitive or specific |
ESR for males __mm/hr | 15 |
ESR for females__mm/hr | 20 |
use a __ top tube for CRP | red |
Correlates well with tissue necrosis or inflammation; positive test indicates the presence, but not cause of the disease; may help predict coronary disease | CRP |
Positive in 60-80% of RA patients, but not specific (also present in health, other autoimmune dz, & chronic infections | Rheumatoid Factor (RF) |
Positive in 70% of RA patients, only 2% of random blood donors; more specific test than RF for dx RA | Anti-cyclic citrullinated peptide (anti-CCP) |
Screening test for connective tissue disorders (pos in SLE, Sjögren’s syndrome, MCTD); titer & confirmatory tests of specific autoantibodies are done if ANA screen positive. | Antinuclear antibody (ANA) |
Useful for diagnosis & follow-up of SLE | Anti-DNA antibody |
typically seen in Wegener’s granulomatosis | C-ANCA |
seen in many forms of vasculitis | P-ANCA |
Diagnostic for sclerodermaPos in 45% of patients with scleroderma | antiscleroderma antibody |
Most commonly performed on knee, but can be done on any involved joint, Used to evaluate monoarticular effusions or when joint disorder etiology unknown, Requires sterile technique to prevent osteomyelitis | arthrocentesis |
arthrocentesis is most commonly done on the __ joint | knee |
culture should include cultures for | Neisseria, Streptococcus, and Staphylococcus |
normal synovial fluid appears | clear and straw-colored |
glucose of normal synovial fluid should be within __mg/dL of plasma glucose concentration | 10 |
normal WBC <__ cells/microL | 200 |
normal RBC <__ cells/microL | 2000 |