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Epidemiology 1
Epidemiology: Derm, Hem-Onc, Renal, Neuro
| Question | Answer |
|---|---|
| Psoriasis | 2.1% of US adults (4.5M); 1M psoriatic arthritis; 200K new cases/yr |
| Achrocordon most common in: | women & obese pts |
| SCC prevalence | 20% of all skin ca |
| Keratoacanthoma epi: | M>F, usually patients >50 yo |
| Most common type of malig melanoma | Superficial Spreading MM (70-80% of all melanoma) |
| Superficial Spreading malig melanoma: Most common in: | Caucasians; usu seen on the trunk and extremities |
| Acral Lentiginous malig melanoma: epi | Most common MM in Asian-Americans / AA (>50% of all melanoma in these pops); Least common type of MM in Caucasians; 7% of all MM; M>F |
| __% of SLE patients have discoid lesions | 25% |
| Skin involvement occurs in __% of sarcoid patients | 25% |
| Rosacea epi | F>M; 30-50 yo; peak 40-50; esp Celtics |
| urticaria/angioedema most common when | 3rd-4th decade |
| scleroderma epi | F>M; 20-50 yrs |
| necrobiosis (NLD) incidence: | 2% of diabetics; female > male |
| Erythema nodosum: epi | 18-30 year olds; F>M; poss assoc w/leukemia |
| psoriasis epi | 2.1% of US adults (4.5M); 1M psoriatic arthritis; 200K new cases/yr |
| pemphigus vulgaris | middle aged; Jewish/mediterranean |
| melanoma numbers | 3% of skin ca; 66% of skin ca deaths |
| Paget dz | 1-2% adults; 5-11% of >80; elderly in NE; FH; 1-3% develop osteosarcoma |
| most common Male cancer | prostate ca (2d M ca COD) |
| thalassemia | alpha: SE Asian, Chinese; beta: mediterranean |
| Sickle cell dz | 8% carry Hgb S gene (trait); 1 in 400 births have SCD; onset in 1st yr (Hgb F falls); 40-50 yr life exp |
| most prevalent leukemia = | CLL: 2:1 M:F; inc w/age; median onset 65 yo |
| CML epi | young & middle age (55 yo); >80% survival 6 yrs |
| Hodgkin dz epi | 2 peaks: 15-45 yo (M>F) & >50 yo; 7900 new cases/yr |
| NHL epi | 20-40 yo; HIV/immunodef or exp to pesticides/solvents; 50K cases/yr |
| G6PD def prevalence | >200M worldwide (usu AA men); X linked recessive; females rare |
| Most common hereditary hyper-coagulable state; mainly ltd to ? | Factor V Leiden; pts of Euro extraction |
| Myelofibrosis peak incidence & survival | 50-70 yrs old; median survival is 2-5 yr from onset; occurs in 10 to 30% of pts w/P. vera |
| Factor IX def prevalence | AKA hemophilia B (Xmas dz); 1:30,000 live births; primarily in males |
| Factor VIII def prevalence | AKA hemophilia A; 1:5,000 live births; primarily in males |
| P. vera: incidence/prevalence | 60-70 yrs (mean dx age 65 yo; rare <40); M:F 1.2:1 |
| esoph ca epidemiology | Squamous cell AA>W (EtOH / tobacco); adenocarcinoma W>AA (Barrett esoph) |
| colorectal ca prevalence | 60,000 d/yr; 3d leading COD |
| bladder ca | 98% are TCC; 3% of ca deaths in US; 3:1 M:F; 40-70 yo |
| most common renal malig: | RCC (renal cell ca): 3% of all adult cancers; usu AA, M, >55 yo |
| most common peds solid tumor: | Wilms tumor |
| most common malig in young men: | testicular ca |
| CKD: 5 yr survival rate = | 35% |
| glomerulonephritis | 60% kids (2-12 yo) |
| most common nephritic syndrome | IgA nepropathy; uncommon in AA, common in Asians; Cirrhosis, Celiac Disease, HIV, CMV |
| ADPKD | most common PKD type (> ARPKD => neonatal M&M, short life exp); usu bilateral; sxs in 4th decade |
| MS epidemiology | F>M; 350K in US (1M world); onset 20-40 yo; most present w/relapsing form; prevalence increases with distance from equator |
| Glioblastoma multiforme (GBM) epi | 50% of Astros; >60 yo; rare <30; 1 yr survival |
| Primary CNS lymphomas: incidence increased in: | Immunodef pts; AIDS; Organ TP; older pt |
| Bell palsy | 60% R sided; more often in PG, DM; assoc w/trauma, infxn, neoplasia, toxins |
| Parkinson dz: epi | 500,000 in US; 58 yo ave onset |
| myasthenia gravis | younger women & older men |
| half of trauma related deaths in young people are: | head injuries |
| Spinal cord injury overall incidence | 4/100,000 per year |
| kidney stones M:F | 3:1 M:! |
| ARPKD prevalence | 1 in 20,000 live births. Often diagnosed in neonatal period |
| Prostate cancer | Most common ca in men (no 2 cause of ca death in men). 160,000 cases/yr. AA>white. |
| Osteoscarcoma | Most common primary malignant bone tumor (20-30% of all). 70% are metastatic or hematologic origin. 3:2 M:F. Mostly adolescents. 2nd peak in 50-60 yo if hx of XRT |
| Anatomic incidence of osteosarcoma | 90% in metaphyseal region of long bones (50% of these around knee). |
| Alzheimer | 60-70% of dementias. 5.3M people in US (to 14M by 2040). |
Created by:
Abarnard
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