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Epidemiology 3
Epidemiology: Rheum, Arthritides, Endocrine
| Question | Answer |
|---|---|
| Sarcoid prevalence | Swedes, Danes, AA; F>M |
| Sarcoid lifetime risk | 0.85% (W); 2.4% (AA) |
| Sarcoid mortality | d/t resp fail = 1-5% |
| SLE epi | US: 15-50/100k (MC AAF); 3x in 40 yrs; 90% F; M = less photosensitivity, more serositis; Elderly: milder dz; 65% 16-55 yo; urban > rural |
| Most common connective tissue disorder involving the esophagus: | Scleroderma esophagus (atrophy & fibrosis of esophageal smooth mx) |
| Polymyositis/Dermatomyositis epi | 2 peaks (kids; >50 yo); very rare; often assoc w/malig (esp DM) & other autoimm dz; PM 3:1 F:M |
| Inclusion Body Myositis (IBM): Epi | In pts >50yrs: most common inflam myopathy; M 2X F |
| Scleroderma Epi | F 3-4 x M; US: 10-20/ million; age, gender & ethnic sig factors in suscept; more common in AA pts; usu 3d / 4th decade |
| Giant cell arteritis Epi | White; >50 yo; F:M = 2:1 |
| polyarteritis nodosa | 3:1 M:F, onset usu 40-60 yo; 30% assoc w/hep B |
| Diabetes Mellitus: incidence of acute life threatening complications | DKA ( 4.6-8 episodes per 1000 pts w/ DM); hyperglycemic hyperosmolar syndrome (HHS: < 1% of all primary DM admissions) |
| Gout epi | M 40-50 yo; F 65 yo; genetic, environmental |
| Prevalence inflammatory arthritis in IBD pts | 30-35% |
| Spondylo prevalence | 2:1000; usu adolescence or early adulthood |
| OA prevalence: | 60-90% of >65; 1 in 5 adults; onset 40-60 yo; 3:1 F:M; knee OA most common cause LT disability in US |
| Inf arthritis incidence | 2-5/100,000 (bimodal: kids, >50 yo) (in RA: 28-38/100,000) |
| Gono arthritis: incidence | 2/3 of infxs arth in pts <40; DGI sequela; F>M (higher risk w/ menses & PG) |
| RA epi | Worldwide: 0.8% adult; 3:1 F:M; peak onset 25-55 yo; 3-5 yr reduction in life exp; Incidence is declining |
| Osteoporosis | F>M (4:1); 1.7M fx in US; 6M hip fx world; W&Asian > Hisp > AA; 4 in 10 WF will fx |
| Androgen-secreting adrenal ca prevalence | More common than adenomas |
| most common thyroid neoplasm | papillary (75-80%); 3:1 F:M, inc w/age; other: follicular, medullary, anaplastic |
| Hypothyroid prevalence | 2% of US F (0.2% US M); 1 in 4000 newborns |
| Graves dz | 6:1 F:M. 20-40 yo. +FH. comorbid w/other autoimmune dz or Addison, celiac, cardiomyopathy |
| Most common cause of hyperthyroidism in US = | Graves dz |
| Most common thyroid disorder in US = | Hashimoto (chronic) thyroiditis: 1% (5% of >65yo); FH, 6:1 F:M, hep C |
| medullary thyroid ca | 1/3 sporadic, 1/3 familial, 1//3 MEN2 |
| Most common Diabetes Mellitus complication | neuropathy |
| Pheochromocytoma | 90% benign, 10% malignant. Found in 0.1-0.5% of HTN pts. May be part of MEN syndromes |
| What % of Diabetes Mellitus pts have T2DM? | 90% (of those, 75-80% associated with obesity) |
Created by:
Abarnard
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