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Vasculitis disorders

Vasculitis Inflammation and necrosis of blood vessels.
Polyarteritis nodosa (PAN) Acute necrotizing vasculitis of medium-sized muscular arteries. Men and whites. Thrombosis/ischemia. Fibrinoid necrosis. Hep B serospositivity 30%.
Kawasaki Disease (mucocutaneous lymph node syndrome) Acute necrotizing vasculitis. Infancy. Fever, rash, conjunctival lesions, oral lesions. Coronary aneurysms. Japan. Self-limiting.
Giant cell arteritis (temporal cell arteritis) Focal. Granulomatous. Temporal artery, aorta. Old age females. Most common vasculitis. Nodular thickening/reduced lumen. Fragmentation of internal elastic lamina. Vision impairment. Polymyalgia rheumatica.
Hypersensitivity angiitis (microscopic polyangiitis, leukocytoclastic vasculitis) Small vessels. Skin or systemic. Palpable purpura. Drugs, infections, tumors. Fibrinoid necrosis, extravasation of RBCs. p-ANCA. Glomerulonephritis/kidney failure.
Churg-Strauss syndrome P-ANCA. Granulomatous. Eosinophilia. Systemic. Young people with asthma/allergies.
Takayasu arteritis. Pulseless disease. Granulomatous thickening of aorta and large branches. Young Asian females. Panarteritis w/giant cells. Steroids/surgical reconstruction.
Thromboangiitis obliterans (Buerger disease) Occlusive. Medium/small arteries. Distal arms/legs. Smokers. Middle-age men. Gangrene. Amputations. Intermittent claudication.
Wegener granulomatosis Systemic necrotizing vasculitis. Granulomatous. Lungs, kidney, upper respiratory. Small vessels. Hematuria/proteinuria. Sinusitis/pneumonitis. C-ANCA. Cyclophosphamide.
Created by: malbrecht