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Pediatric Pance
| Question | Answer |
|---|---|
| Acute otitis media | MC infx in peds S pneumoniae --> #1, H influenzae, Moraxella catarrhalis -also viruses: influenza A, RSV, parainfluenza RF: straight eustachian tube, day-care, smoking Ssx: dull bulging immobile TM, poor feeding, irritable |
| Treatment of Otitis Media, and complications | -high dose amoixicillin x 10 d empiric -complications: TM perforation, mastoiditis (Hflu), meningitis, cholesteatomas, chronic otitis media |
| Serous OM | associated with allergic rhinitis FLUID in middle ear w/o acute infix decreased mobility of TM Tx: observation and decongestants x3mo NO ABX consider drainage >3mo to avoid hearing/speech delay |
| MCC bronchiolitis | RSV |
| MCC Croup | Parainfluenza |
| Bronchiolitis features | -child<2 yo, fall winter -inflammation small airways upper and lower resp tract -tachypnea, wheezing, crackles, -inc respiratory rate |
| Bronchiolitis treatment | -supportive: nebulizer, hydration -high risk pt: maybe Ribavirin, RSV prophylaxis w/ Respi-Gam or Synagis |
| Croup pathophys | -aka laryngotracheitis/ layrngotracheobronchitis -inflammation of the larynx w/in the sub-glottic space |
| Croup symptom/diagnosis | -barky cough at night, inspiratory *stridor* -prodrome 1-7 days, URI symp -stridor improves with racemic epinephrine -Neck XR: subglottis narrowing (steeple sign) |
| Treatment of Croup based on severity | -mild: cool mist tx, fluids -moderate: supp O2, IM corticosteriods, nebulized racemic epinephrine -severe: inpt, nubulized racemic epinephrine |
| epiglottitis features, CXR, pathogens | -Streptococcus spp (H influenza type b, now immunization) -*acute onset high fever*,*Respiratory distress*: drooling, dysphagia, inspiratory retractions, neck hyperextension, sniffing dog position -XR: swollen epiglottis, "thumbprint sign" |
| epiglottitis diagnosis and treatment | -emergency! Secure the airway! -evaluate with ENT or anesthesiologist -definitive diag with fiberoptic visualization of cherry red epiglottis -intubate, IV ceftriaxone/cefuroxime |
| MCC meningitis in neonates (<1 month) | GBS, Listeria, Ecoli Tx: ampicillin + gentamycin Ampicillin is for LISTERIA Gentamycin will cover GBS and Ecoli |
| MCC meningitis infants/children | S pneumoniae, N meningitidis, H influenza |
| Meningitis associated with petechial rash | N meningitidis |
| Treatment of meningitis in neonate (<1 month) | -ampicillin and ceftaxime or gentamicin (no ceftriaxone for neonates) -bugs: GBS, Listeria, Ecoli |
| Treatment of meningitis in infant/child | -ceftriaxone and vancomycin -bugs: S pneumo, H influenza, N meningitidis |
| Treatment of pertussis | -hospitalize infant< 6 m macrolides (erythromycin / azithromycin) |
| Daignosis pertussis | CULTURE it! suspect if WHOOPING inspiration |
| Diagnosis, Treatment of hemophilia | -prolonged PTT, normal prothrombin, bleeding time, fibrinogen level, low factor VIII -tx: replace factor VIII; mild disease: desmopressin (DDAVP) releases factor VIII from endothelial cells |
| Enuresis treatment | 1. reassurance, resolves spontan, normal 4-5 yo 2. *desmopressin* (DDVAP) 3. imipramine |
| Ewings sarcoma pathophys, genetics | -sarcoma (neuroectoderm) -chrom 11:22 translocation -Caucasian males |
| Ewings sarcoma features, XR | -*systemic symptoms* (none in osteosarcoma) + local pain, swelling -midshaft of long bone = middle of FEMUR -*inc ESR* -XR: onion skin, periosteal reaction |
| Osteosarcoma pathophys | -osteoblasts (mesenchyme) -male adolescents |
| Osteosarcoma symptoms, features, XR | -*local symp only* (v Ewings: sysemic sx) -metaphysis long bones = distal femur -metastasis lungs 20%--> get CXR!! -*inc alk phos* -"sunburst lytic lesion |
| Management of unilateral gynecomastia in adolescent male | -Pubertal gynecomastia: seen in 50% adolescent boy ~14 yo -usually asymmetrical, tender, regresses in 6-18 months -ass w/ inc adrenal androgens, more can convert to estradiol -tersticle size usually 2cm lngth, 3mL volume |
| MCC of stridor in children | traceomalacia/laryngomalacia: -floppy epiglottis, disproportionately small soft larynx -noisy breathing, worse with lying on back (gravity) -larygoscopy: collapse of laryngeal structures during inspriation -no treatment needed, resolves by 18 months |
| vitamin supplement fr measles | vitamin A -reduces morb/mort; immune enhancement, allows GI and respiratory epithelium to regenerate |
| complications with varicella | -skin lesions 2/2 infection w/ Strep pyogenes or Staph aureus -pneumonia, encephalitis -Reyes syndrome (w/ aspirin use) |
| Treeatment for varicella in normal child, or VZV pneumoniae | -normal child: antihistamines, lotions -immunocompomised child or VZV pneumoniae: acyclovir |
| Treatment for immunocompromised child/newborn exposed to varicella | -Varicella zoster immune globulin (VZIG) |
| Measles (Rubeola) cause, prodrome, rash features | -paramyxovirus -Prodrome: Cough, coryza, Conjunctivitis -*koplik spots* -rash: maculopapular rash head-->toe |
| Rubella cause, prodrome, rash | -rubella virus "3-day measles" -Prodrome: low grade fever (v measles) LAD behind ears -rash: maculopapular head-->toe (but clears on its way down) |
| 2 yo boy w/ 3 days of very high fever. Fever resolves, child breaks out into diffuse rash on trunk--> extremities | Roseola infantum -HHV-6, HHV-7 -cx febrile seizures |
| Erythema infectiosum (fifth disease) cause, rash, complications | -Parvovirus B19 -"slapped cheeks", itchy erythematous rash arms-->trunk; *worse* with sun and fever -cx: aplastic crisis in sicklers Once have rash on body = no longer infectious, but very contagious prior to that during slapped cheeks phase |
| MCC nephrotic syndrome in children | -Minimal change disease--> give empiric steroids -child with edema, proteinuria>3.5, hyperlipidemia |
| Minimal change disease diagnosis, treatment | -diagnosis made clinically -give empiric steroids -no biopsy needed |
| Contraindications to DTaP | -immediate anaphylactic reaction, encephalopathy, CNS complication w/in 7 d --> give DT instead of DTaP -adverse reactioins attributed to *pertussis* component of vaccine |
| newborn chokes, coughs regurgitates with first feeding; +- atelectasis | esophageal atresia w/ or w/o tracheoesophageal fistula (air in esophagus and stomach; food in lungs) |
| 3 weeks-5 month old infant with 5 days of non-bilious vomiting after feeds; olive shaped mass in midepigastrum; peristalstic waves in epigastrum | hypertrophic pyloric stenosis -idiopathic, not present at birth |
| Newborn with bilious vomiting w/o abdominal distention | duodenal atresia -ass w/ down syndrome -XR: double bubble sign -tx: NG decompression and fluids; duodenoduodenostomy |
| Fetal alcohol syndrome defects | -midfacial hypoplasia, hypoplastic maxilla, long philtrum, thin upper lip border, microcephaly -irritable, MR |
| Lithium birth defects | congential heart dz (Ebstein's anomaly) |
| Warfarin birth defects | nasal hypoplasia, stippled bone epiphyses, developmental delay, ophtho anomalies |
| Valproic acid birth defects | neural tube defects (spina bifida) |
| Down syndrome features, associations | -meitotic nondisjunction (95%) -upslaneted eyes, simean crease, hypotonia -duodenal atresia, Hirschprungs, congenital heart dz (ASD, endocardial cushion defect>VSD) -inc risk ALL, hypothyroidism, early onset Alzheimers |
| Klinefelter's syndrome (male) features | 47XXY hypogonadism testicular atrophy, tall stature, long extremities, gynecomastia, female hair distribution |
| Turner's syndrome (female) | -45XO MCC primary amenorrhea due to ovarian dysgenesis (dec estrogen) webbed neck, coarc aorta, lymphedema hands feet as neonate -horshoe kidney |
| Fragile X syndrome | X-Dominant --> MALES -MC inherited form of MR -large jaw, large testes, laarge ears -autistic behavior |
| Palpable purpura | Henoch-Schonlein purpura |
| Henoch-Schonlein Purpura is associated with what complciation? | Intussusception: due to intestinal wall purpura -abd pain and large amount of blood in stool |
| Most comon cause of bowel obstruction in first years of life | intussusception |
| Risk factors for Intussusception | -Meckel's diverticulum -intestinal lymphoma -Henoch-Schonlein purpura -celiac dz, CF, infxnx, polyps |
| Intussusception features, diag, tx | -abrupt onset colicky abd pain, comiting, bloody mucus in stool (currant jelly stool) -"suasage shaped" RUQ abd mass -no bowels in RLQ -diag: US: target sign -emergency: air-contrast barium enema |
| acid base in pyloric stenosis | -hypocholremic, hypokalemic, metabloic alkalosis (vomiting HCl) |
| Meckel's diverticulum sx, diag, tx | -child <2 yo -sudden intermittent painles rectal bleeding -cx: intestinal obstruction, diverticulitis, volvulus, intussusception -diag: Meckel scintigraphy scan -tx: surgical excision of the diverticulum with adj ileal segment |
| Hirschsprung's disease path | -no ganglion cells in distal colon, uncoordinated perstalsis -ass w/ Down syn, MEN type 2, Waardenburg |
| MC GI emergency in neonates, esp premature infants | Necrotizing Enterocolitis |
| XR: pneumatosis intestinalis (intramural air bubbles, gas produced by bacteria w/in bowel wall) | Necrotizing Entercolitis |
| Gastroschisis | -bowel protrudes through defect on R side umbilical cord -no cover on membrane -bowel angry and matted -no ass w/ other abnormalities |
| Omphalocele | -intraabd contents protrude through umbilical ring -bowel covered by amnioperitoneal membrane -ass w/ other congential abnormalities |
| Management of Gastroschisis and Omphaocele | -delivery at tertiary care center -C-sec only for usual indications -wrap bowel with sterile dressing (gastro and omphalo) preserve heat and dec fluid loss -insert orogastric tube to decompress tomach -stabilize airway, IV access |
| disease association with ASD and endocardial cushion defects | Down syndrome |
| congenital infection ass w/ PDA | congential rubella triad of congenital rubella - PDA - hearing defect - cataracts Blueberry muffin baby |
| dz ass w/ coarctation of aorta | Turner's syndrome -can also have biscuspid valve |
| Disease associated with coronary artery aneurysms | Kawasaki disease |
| Disese ass w/ congenital heart block | neonatal lupus |
| dz ass w/ supravalvular aortic stenosis | Williams syndrome - elfin face, neurodevelopmental do |
| dz ass w/ conotruncal abnomalities (truncus arteriosus, tetrology of fallot, interrupted aortica arch) | CATCH-22 syndromes, Gi-George, velcardiofacial syndromes |
| Ebstein's anomaly | Maternal lithium use during pregnancy |
| dz as w/ asymmetric septal hypertrophy and transposition of the gerat vessels | maternal diabetes |
| Neisseria v Chlamydia and sexual abuse | -Neisseria in vaginal culture is defnitive evidence of abuse -Chlamydia is not bc can be from mother during delivery and can persist for up to 3 yrs |
| acyanotic heart defects and their murmurs | -rarely present at birth; L-R shunt VSD - harsh holosystolic murmur ASD- fixed wide split S2, sys ej murmur PDA - machinery, wide pulse P, bounding pulses |
| Eisenmenger syndrome | -left to righ shunt leads to pulmonary hypertension and shunt reversal |
| Most common cyanotic heart disease in new born v child | -newborn: transpositsion of great vessels -child: tetrology of Fallot |
| congential heart disease nitially tereated with PGE1 | PGE1 keeps ductus arteriosus from fetal circulation OPEN until neonate stable enough for surgery -severe coarctation of aorta -transposition of great vessels -tetrology of fallot |
| Anomalies in Tetrology of Fallot | PROVe Pulmonary stenosis RVH Overriding Aorta VSD |
| treatment of VSD, ASD, PDA | -VSD: tx CHF w/ diuretics, inotropes, ACEI; small VSD close spon; large VSD, surgery -ASD: 90% close spon -PDA: indomethacin unless needed for survival (transposition, tetrology) |
| Milestones 2 months: gross motor, fine motor, language, social | -*lift head/chest when prone* -track pst midline -coos -*social smile* |
| Milestones 4-5 months: gross motor, fine motor, language, social | ROLLS OVER grasp - can hold rattle laughts |
| Milestones 6 months: gross motor, fine motor, language, social | -*sit unassisted* palmer grasp, transfer objects -*babbles* -*stranger anxiety* Transfer across midline |
| Milestones 9-10 months: gross motor, fine motor, language, social | -crawl, pull to stand -pincer grasp -nonspecific "mama/dada" -waves bye bye, pat-acake |
| Milestones 12 months: gross motor, fine motor, language, social | -*walks alone* -2 finger pincer grasp -*1-3 words*; follow *1 step commands* -*separation anxiety* imitates |
| Milestones 2 years: gross motor, fine motor, language, social | -*walks up/down stairs*, jumps -tower of 6 cubes -*2-word phrases* -follow *2step commands* |
| Milestones 3 years: gross motor, fine motor, language, social | -*tricycle*; climb stairs with alternating feet -*copies a circle* -*3 word sentences* -brush teeth, wash/dry hands |
| Milestones 4 years: gross motor, fine motor, language, social | -hop -*copies a cross* -knows colors, some numbers -cooperative play, board games |
| Milestones 5 years: gross motor, fine motor, language, social | -skips, walk backwards -*copies triangle* -*5 word sentences* -domestic role playing, dress up |
| Cerebral palsy management | -no cure -treat spasticity with diazepam, dantrolene, baclofen |
| Febrile seizure diagnosis, tx | -focus on finding source of infection -LP is CNS infection suspected -no w/u if >18 m and its obviously febrile seizure -<6 m need sepsis w/up -tx: acetominophen; no aspirin (Reyes) |
| Signs of autism in development milestones | -no babbling, gesturing by 12 months -no single words by 16 months -no 2 wordphrases by 24 m -failure to make eye contact -other signs of language or social skills |
| Umbilical hernia management | -imperfect closure, weakness of the umbilical ring -most disappear apon by 1 yo -surgery if hernia persists to 3-4 yo, exceeds 2 cm diameter, symptomatic, becomes strangulated, or progressively enlargens after 1-2 yo |
| meconium ileus | -manisfestaion of CF -failure to pass meconium w/in first 24 hours of birth -bilious vomiting -h/o polyhydramnios -family history of CF -cx: intestinal perforation--> pneumoperitoneum (after birth) or intrabdominal calification (before birth) |
| Meconium plug syndrome | -similar presentation to meconium ileus: bilious vomit, failure to pass meconium w/in first 24 h -BUT non-cystic fibrosis babies -no cx with intestinal perforation |
| child with anemia, thrombocytopenia, renal failure | Hemolytic uremic syndrome |
| Most common cause of acute renal failure in toddlers | HUS 2/2 E coli 0157:H7 -tx: supportive with plasmapheresis, maybe dialysis and steroids |
| *infant cyanotic when feeding, sucking; relieved by crying* | Choanal atresia -separation of the nose and pharynx by a membrane or bone -unable to pass catheter through one or both nostrils -confirm diag with CT scan with intranasal contrast -tx: place oral airway and lavage feeding; surgery |
| Laryngomalacia | --month olg infant, noisy breathing, stridor, hoarseness, symptoms worse when lying on back -floppy epiglottis and supraglottic aperture; small and soft larynx -tx: reassurance, rsolves spont in 18 m |
| Wiskott-Aldrich syndrome | -Xrec, males -*low IgM*, high IgE, IgA, *thrombocytopenia* -*bleeding, eczema, recurrent otitis media* -present at birth with bleeding from circumcision, petechiae, bruises, bloody stool -infxnx encapsulated organism |
| Dactylitis | -hand foot syndrome -6m-2 yo acute onset symmetric swelling of hands and feet, due to vascular necrosis of metacarpals and metatarsals -earliest sign of vaso-occlusion insickle cell anemia -give child complete w/up |
| recurrent hemarthroses (bleeding into joint) | Hemophilia |
| Tay-Sachs disease | -lysoomal storage disease; abscence hexoaminidase leads to GM2 ganglioside -normal until 3-6 months old -cherry red spot but *NO hepatosplenomegaly* -Tay-SAX lacks heXosaminidase |
| Legg-Calve-parthes disease | AVASCULAR necrosis of femoral head 2-8yo Ssx: painful limp Tx: rest and NSAIDS then hip surgery |
| Slipped capital femoral epiphysis | displacement of femoral epiphysis OBESE adolescent Ssx: painful limp and externally rotated leg |
| Osgood-Schlatter disease | overuse apophysitis of tibial turbercle -loaclized pain, esp quadriceps contraction -in acitve young boys -tx: dec activity 3 months, maybe a brace |
| complications of duchennes muscular dystrophy | -mortality from pulmonary congestion caused by high output cardiac failure stemming from cardiac fibrosis |
| Neonatal conjunctivitis | -present w/in 24 hrs of life: chemical conjunctivitis due to silver nitrate; resolves spont -presents on 2nd day of life: gonococcal; most destructive; ceftriaxone -presents day 5-14: chlamydia; oral erythromycin |
| daignosis of ALL | -CBC, blood smear: 90% lymphoblasts, WBC count low, norm or high -bone marrow aspirate for hypercellularity and blasts -*CXR to r/o mediastinal mass* |
| Tumor lysis syndrome | -hyperK, hyperphosphatemia, hyperuricemia -comon prior to and during chemo tx -tx with fluids, allopurinol, urine alkalinization -corticosterios CI bc can pricipaitate tumor lysis syndrome |
| Neuroblastoma | -neural crest tumor -<2 yo ass w/ neurofibromatosis, Hirschsprungs disease, M-myc oncogene -sx: nontender abdominal mass *crosses the midline*, Horners syn, *myoclonus* -*elevated VMA and HMA* |
| Freidrich's ataxia | gait disturbances, pes cavus, ataxia, absent ankle reflexes |
| Peutz-Jeghers syndrome | GI tract polyposis, mucocutaneous pigmentation -estrogen secreting tumor: precocious puberty |
| Sturge Weber | port-wine stain over trigeminal nerve eye / vision involvement MR SEIZURES |
| Atlantoaxial instability | -1-2% Down syndrome pts with upper motor neuron findings -increased laxity C1 and C2--> compressionof spinal cord |
| dermatitis herpetiformis and chronic non-bloody diarrhea in child 12-15 months | celiac disease |
| young child with recurrent upper respiratory infections and bilateral nasal polyps | cystic fibrosis |
| Sickle cel disease patients are susceptible to infection from what bugs? | -functional asplenia by 2-3 yo, can't remove encapsulated organisms -Pneumococcus (Strep pneumo) -H. influenza -osteomyelitis: Salmonella |
| *Marfans syndrome* | -Aut dom -mutation fibrilin-1 gene (v collagen Ehlers-Danlos) -tall stature, emaciated extremities, arachnodactyly, hypermobility of joints, *upward lens dislocation* (v downward in homocyst), *aortic root dilation* |
| Ehlers Danlos | -defective *collagen* production (v Marfans- fibrillin) -hypermobile joints -easy bruising, poor wound healing, velvety hyperelastic skin -cx: organ rupture, hemorrhage |
| Treatment of Kawasaki disease | aspirin and IVIG -only time it is ok to give child aspirin |
| PKU | -aut rec -def phenyalanine hydroxylase - breaks down phenyalanine into tyrosine -screening: check blood phenyalanine test -Guthrie test in urine- qualitative test |
| Heinz bodies | -aggregates of denatured Hb seen in G6PD def, thalassemia -bite cells also seen |
| Physiologic jaundice | -not present until 72 hrs after birth, lasts 1 week -moderate unconj bili<12-14 -more common in preterm, diabetic mom, Asian pts |
| Breast milk jaundice | -appears in 2nd week of life -unconj bili ~10-30 -levels drop rapidly when breastfeedig stops; give formula 1-2 d, and return to breastfeeding |
| Pathologic jaundice | -appears in first 24-36 hrs of life, lasts longer than a week -direct/conj bili >12; inc >5/day |
| Henoch-Schonlein Purpura | -IgA vasculitis of small vessels -follows strep or viral URI -sx: palpable purpura, arthritis, abd pain -cx: intussusception, renal dysfunction (IgA deposition) -tx: usually benign, self limited; severe: steriods |
| Downs Syndrome child with loud P2. What heart defect? | Endocardial cushion defect of AV canal - left to right shunt leads to pulmonary hypertension (v ASD - low flow to lung) |
| Benign mumur features = still's murmur | -most murmurs in children are benign: asx pt, intensity grade 2 or less, normal S2, no clicks, normal pulses - LSB systolic low grade - diminishes with standing, sitting, or valsalva - loudest when laying down |
| Pathologic murmur features | -most murmurs in children are benign -Pathologic need echo: symptomatic, intensity 3 higher, abnormal S2, pansystolic, no femoral pulses, murmur quality unchanged with position |
| Calculate Apgar | -Color:0 blue; 1 body pink, ext blue; 2 pink -HR: 0 no act; 1 <100; 2 >100 -Reaction: 0 no reaction; 1 grimace; 2 active cough -Tone: 0 limp; 1 some flexion; 2 active flexion -Respirations: 0 none; 1 slow; 2 good effort |
| premature infant with normocytic, normochromic anemia; no other RBC abnormalities on peripheral blood smear (no schistocytes); reticulocyte count low | -Anemia of prematurity - commo in premature infants and low birth weight infants -diminished RBc prod, short RBC life span and blood loss -tx: iron supplementation although anemia unrelated to iron def |
| strawberry tongue and sandpaper rash | scarlet fever |
| Scarlet fever path, sx, tx | -toxin mediated dz by Group A Strep -fever, 12 hrs later punctate pink exanthem on trunk --> extremities -fades in 4 days followed by desquamation -pharynx is beefy red, tongue initially white, then bright red -tx: pencillin V> erythromycin, clinda |
| Stevens Johnson Syndrome sx, tx | -severe variant of erythema multiforme -erythema multiforme lesions (traget lesions) covering *<10% body*--> bullae -fever malaise, *mucous membranes involvement*, uveitis -due to virus (herpes) or drugs -supportive tx |
| Toxic Epidermal Necrolysis | -severe erythema multiforme with widespread involvement -due to drug hypersensitivity -target lesion--> widespread full thickness necrosiss of skin >30% body -prodrome fever, flue sx -mucous membranes affected |
| Hand Foot Mouth disease | -coxsackie A virus -vesicles open rapidly to painful ulcers, even in soft palate -gray blisters on hands, feet, on background erythema -high fever, severe sore throat, may be unable to swallow -ulcerative lesions on palate, tonsils, pharynx |
| MC presentation of sickle cell trait | painless hematuria -sickle cell DISEASE: acute painful episodes, splenic infarction, dactylitis, etc |
| Congenital Toxoplasmosis sx | -chorioretinitis -hydrocephlus -intracranial Calcifications -ring enhancing lesions on MRI -tx pyrimethamine and sulfadiazine |
| Congenital Rubella sx | -"blueberry muffin rash" -cataracts -MR -Hearing loss -PDA |
| Congenital CMV | -*periventricular* calcifications -petechial rash |
| Congential HSV | -skin eye mouth infections -CNS/systemic infection -acyclovir |
| Congenital HIV sx | -often asx -failure to thrive -bacterial infexns -inc incidence of upper and lower resp diseases |
| Congenital Syphlis sx | -snuffles -maculopapular skin rash -LAD, hepatomegaly osteitis -late congential syphilis: saber shins, saddle nose, CNS, Hutchinsons triad (peg shaped incisors, deafness, interstitial keratitis) |
| nocturnal vulvar itching, anal pruritis | pinworm infection -scotch tape test -mebendazole |
| Lyme Disease treatment in children | -<9 yo, preg women: amoxicillin ->9 yo: doxycycline -if cannot take amox or doxy, give cefuroxime or erythromycin |
| social smile | 2 months |
| 6 months | babble start teething Transfer objects across midline Sits up unsupported |
| 2-3 words phrases, obey 2 step commands | 2 yo over 50 word vocal |
| hold head up | 3 month |
| roll back to front and fron to back | 4 months |
| walk up and down stairs without help | 24 months |
| 9 months | bangs 2 objects together |
| 12 months | FINE pincher starts walking 2-3 words and can obey 1 step commands |
| 15 mo | build tower of 2 blocks walks independently 3-5 words |
| 24 months | builds tower of 6 cubes turns page of books jumps in place |
| imitates action/comes when called | 12 months |
| play with other children | 18 months old |
| Supracondylar humeus fracture | -most comon pediatric elbow fracture -danger of brachial artery entrapment - *do radial pulse test* -inc risk Volmann's contracture: compartment syndrome of the forearm |
| *TCA intoxication treatment* | -sodium bicarbonate for QRS prolongation -diazepam or lorazepam for seizures -cardiac monitoring for arrhythmias |
| Todd's paralysis | hemiparalysis right after a seizure -postictal paralysis -restoration of function in 24 hrs |
| Iron poisoning sx | -nausea, vomiting, diarrhea, abd pain, GI bleeding, metabolic acidosis -iron pills radio-opaque, CAN be seen on abd XR -tx: asymptomatic pt: ipecac syrup symptomatic: deferoxamine, an iron chelator |
| MCC of death by poisoning | multivitamin pills - iron toxicity |
| *aseptic necrosis of the femoral head* | -common coplication of sickle cell disease -sx: pain in the hip that gradually progresses -involves occlusion of end arteries supplying the femoral head, bone necrosis and eventual collapse of the periarticular bone and cartilage |
| Waterhouse-Friderichsen syndrome | -sudden vasomotor collapse and skin rash (large purpuric lesions on flanks) due to adrenal hemorrhage -esp after infant with meningococcemia RF: meningococcal meningitis |
| IgA type B cell deficiency predisposes to what infxnx? | Giardia!!! -cannot kill encapsulated prgaisms, so also H influenza and S pneumo |
| Erythema toxicum | -benign self limited condition in *newborns* -evanescent rash with red halos and *eosinophils* on skin lesions |
| Hirschsprung v Intestinal atresia | BOTH: bilious vomit, no BM hirsch: *48 hrs* eval - no meconium atresia: duodenal atresia (double bubble), jejunal stresia (triple bubble); immediate eval of newborn |
| Bronchopulmonary displasia (BPD) | chronic lung disease from infants that needed MECHANICAL vent and supplemental O2 for RDS (resp distress synd) Defined as need for supplemental O2 after 36 wks PE: tachypnea, increased AP diameter, air trapping |
| TORCH infections | Prenatal infex that lead to severe abnormalities = most common HEARING IMPAIRMENT & MR Toxoplasmosis Other = syphillis, varicella, HIV Rubella Cytomegalovirus Herpes Simplex |
| Live vaccines | Influenza live in NASAL SPRAY ROTAVIRUS VARICELLA / zoster RUBELLA MMR |
| DTaP vs. Tdap | Diphtheria + Tetanus + acellular Pertussis = DTaP given in 5 doses: 2, 4, 6, 15mo, 4 yrs Tdap is the BOOSTER given to children ~10yo who did not complete DTaP series Td BOOSTER given q 10 years - can give to adults |
| Vaccines at 12mo | MMR Varicella Hep A (hep B can give at birth) |
| Vaccines that cannot be given in prego | MMR Rubella Varicella / zoster |
| infant growth | head circumference increases 1cm/mo 1st year 2cm total 2nd year birth wt triples by year 1 |
| female sexual development | onset of secondary sexual characteristics 8-13yo Breast budding is the first sign Menarche w/in 2 years of budding |
| mom of neonate is HBsAg+ | give HepB IgG to neonate |
| Meningitis in the neonate | Vertical transmission from GU/GI tract of mom MCC = Grp B strep - prophylax mom @ delivery with AMOXICILLIN |
| Respiratory distress syndrome (RDS) | Due to insufficient surfactant RF: premature, meconium aspiration Prevent: steroids to preterm Ssx: tachypnea, tachycardia, retractions, grunting, cyanosis, nasal flaring Dx clues: HYALINE mb in alveoli/ground glass appearance on CXR |
| Meconium aspiration | Normal fetus does not release meconium until after birth If meconium is released in amnionic fluid, the fetus can aspirate --> meconium inactivates surfactant and leads to RDS Clinical PE: infant is stained with meconium @ delivery CXR: ground glass |
| SIDS | sudden unexplained death highest in winter / males 2-6mo RF: teen mom, preterm / low birth wt / smoking exposure Prevention: breastfeeding, BACK to SLEEP |
| Neonatal physiologic jaundice | Increased in indirect / unconjugate bilirubin COOMBs negative appears on 2-3d, peaks by 5d, gone by 7-10d Due to liver immaturity (not conjugating) Tx: PHOTOTHERAPY |
| Pathologic jaundice | w/in 24 hours of life Coombs POSITIVE = suspect hemolytic disease of newborn due to ABO incompatibility |
| Breast-milk jaundice | Associated with breast-feeding Peaks by 14d Increase in INDIRECT bilirubin Diagnosis of exclusion when other causes of jaundice r/o |
| Herpangina | Coxsachie A virus = hand, foot, mouth disease Ssx: multiple small ulcers/vesicles on posterior pharynx and on fingers + FVR, dysphagia RF: fecal-oral transmission from swimming pools / water parks self-limiting. no complications |
| Reye's syndrome | caused by use of ASA for VIRAL illness Ssx: rash, vomiting, lethargy, encephalitis, coma BUT ASPIRIN is ok for KAWASAKI d/o |
| Septic arthritis in peds | MCC < 15yo = staph aureus MCC >15yo = nisseria gonorrhea FVR, pain, swelling, limited joint motion Tx: MUST TAP = arthrocentesis + IV abx |
| Roseola infantum | acute viral disease = HHV6 + HHV7 Ssx: starts with FUO 3-5d with no other clinical signs. When FVR drops get significant rash spreading from trunk outward Key: if rash and FVR at same time = not roseola Ddx: Rubella Rubeola (measels) |
| abrupt onset of FVR in peds with no other signs, followed by rash | Roseola Very high FVRs in roseola = febrile seizure risk |
| Congenital rubella | TRIAD: cataracts, deafness, heart defects PE: blueberry muffin baby |
| peds rashes | 1. FVR then rash = roseola 2. head cold/photophibia + FVR, then rash + FVR = meseals 3. Sandpaper rash, finely papular = scarlet fvr 4. slapped cheeks then rash = erythema infectious 5. dew drop on a rose petal = varicella |
| Scarlet FVR clues | 1. Sandpaper papular rash 2. Strawberry tongue 3. Pastia's lines = rash in flexor creases does not blanch esp axilla and groin Ssx: acute onset FVR, sore throat, chills, hypermic tonsils, exudates Tx: penicillin, amoxicillin |
| Salicylate poisoning | causes anion-gap metabolic acidosis Tx: maintain hyperventilation to compensate (pt on vent) Activated charcoal if <2hrs Correct fluid deficits to get urine output 1-1.5ml/kg/hr ALKALINIZE URINE (bicarb bolus) - prevents salicylate reabsorption |
| neonatal septic workup | Get LP on any febrile neonate <28d Otherwise LP any infant with CNS signs (irritability, lethargy) MCC: GBS, E/coli from maternal GU tract Dx: LP, blood culture, urine culture, CXR Tx: ampicillin and gentamycin |
| 6mo infant brought in by mom for seizure, FVR 103 x 3d. On PE irritable, shallow breathing, delayed cap refill, BP 80/20 | most likely dx = FEBRILE SEIZURE 2/2 SEPSIS must order septic eval: CBC + D CSF analysis blood / urine cultures CXR |
| Varicella | HIGH pruritic rash that is vesicular best initial test = TZANCK smear showing multinucleated giant cells Tx: supportive, antihistamines to decrease itching Cx: staph aureus super-infection Prevention: vaccine at 12 mo |
| peritonsilar abscess | UVULA is not midline - deviates away from abscess Hot potato voice MCC = GABHS Tx: ceftriaxone + drainage (always drain abscess) Cx: can cause obstruction around carotids |
| Vaccines given at 2, 4, 6, & 15mo schedule | CHID conjugated pneumo H flu Inactivated polio DTaP |
| Muscular dystrophy | X-linked Progressive degeneration of skeletal muscle GOWLER maneuver to stand dead by 25 from respiratory failure |
| Absence seizure | School age 5-12 peak incidence NO POST ICTAL PERIOD Amnesia after each seizure Ssx: sudden stare, stop verbal/motor activity "day dreaming" "impairment of consciousness" Tx: ethosuximide |
| Tonic-clonic seizure | Grand mal = associated with Epilepsy MC type of seizure d/o Ssx: frequently aura, HA, amnesia Jacksonian march = seizure is generalized Todd's paralysis = weakness in post-ictal period Tx: anticonvulsants |
| Status epilepticus | Prolonged seizure > 30 min w/o regaining CNS funx risk of brain damage from hypoxia Tx: intubate / airway support 2 IV O2 mask Lorazepam (1st choice) Fosphenytoin Send labs for TOX screen, metabolites, sepsis workup |
| Infectious diarrhea in peds | Bloody stools and + cultures (E.coli / shigella) = do not use ABX - will cause the bacteria to release toxins In peds tx all diarrhea with aggressive fluid rehydration and caloric support No opiates (loperamide) for infx diarrhea ever |
| Tinia capitis | Peak = school age kids Superficial fungal infx of the scalp = scalp ringworm Ssx: scaling, erythema, partial alopecia, itching, red raised patches Tx: ORAL GRISEOFULVIN unlike other tinia this one does not respond to topicals, must give PO |
| Head lice | due to direct contact / sharing hats Ssx: Nits are firmly attached white lesions (vs. dandruff) Tx: Permethrin Must re-treat 1 week later |
| Hemophilia A vs. B | A = factor VIII defect Tx: cryoprecipitate B = factor IX defect Tx: FFP - there is no factor IX in cryoprecipitate Both types give hemearthrosis and increased PTT |
| Hemorrhagic disease of the newborn | gut is not colonized so bacteria are not making VitK Give VitK IM shot immediately after birth |
| Hemolytic uremic syndrome | follows acute gastroenteritis E.Coli infection releases toxins Ssx: TRIAD follows episode of diarrhea - hemolytic anemia - jaundice - thrombocytopenia - petechiae - acute renal failure - oliguria, edema, HTN Tx: SUPPORTIVE No abx for HUS |
| ALL | #1 childhood malignant neoplasm Ssx: initially non-specific - generalized weakness, fatigue, wt loss - pallor, bruising, petechiae - FVR - increased infx - SWOLLEN lymph nodes, spleen enlargement - bone pain 2/2 marrow hypertrophy |
| Hemangioma | MC BENIGN childhood neoplasm |
| GI foreign body | remove if in the esophagus = endoscopy Ssx: may be asymptomatic - can swallow liquids but difficulty with solids - copious DROOLING in toddlers |
| retinopathy of prematurity | disorganized retinal vessels in premeeis that had NICU stays likely due to overexposure to supplemental O2 RF: - premature - O2 |
| 7yo presents with NO IMMUNIZATIONS, which are the most appropriate to start with | Tdap, polio (OPV), measles-mumps-rubella (MMR) children not immunized in the 1st year of life and you are >7yo = give Tdap (not DTap) |