click below
click below
Normal Size Small Size show me how
IBD
Inflammatory Bowel Disease
| Characteristic | IBD |
|---|---|
| Disordered response to intestinal bacteria | Crohn's |
| Autoimmune etiology | Ulcerative colitis |
| Rectal sparing | Crohn's |
| More commonly involves ileum | Crohn's |
| Skip lesions | Crohn's |
| Continuous lesions | Ulcerative colitis |
| Rectal involvement | Ulcerative colitis |
| Cobblestone mucosa | Crohn's |
| Transmural inflammation | Crohn's |
| Mucosal & submucosal inflammation only | Ulcerative colitis |
| Friable pseudopolyps with freely hanging mesentery | Ulcerative colitis |
| Creeping fat | Crohn's |
| String sign on barium swallow | Crohn's |
| Lead pipe appearance due to loss of haustra | Ulcerative colitis |
| Linear ulcers, fissures, and fistulas | Crohn's |
| Right lower quadrant pain | Crohn's |
| Left lower quadrant pain | Ulcerative colitis |
| NOD2 mutation association | Crohn's |
| Noncaseating granulomas | Crohn's |
| Lymphoid aggregates | Crohn's |
| Crypt abscesses | Ulcerative colitis |
| Ulcers and bleeding without granulomas | Ulcerative colitis |
| Th1-mediated response | Crohn's |
| Th2-mediated response | Ulcerative colitis |
| Perianal disease | Crohn's |
| Primary sclerosing cholangitis | Ulcerative colitis |
| Toxic megacolon | Crohn's |
| Bloody diarrhea more common | Ulcerative colitis |
| Migratory polyarthritis | Crohn's |
| Erythema nodosum | Crohn's |
| Pyoderma gangrenosum | Ulcerative colitis |
| Sometimes p-ANCA positive | Ulcerative colitis |
| Renal calculi | Crohn's |
| Recurs after surgery | Crohn's |
| Treated with colectomy | Ulcerative colitis |
| Collections of neutrophils within crypts of Leiberkuhn | Ulcerative colitis |
| Regional enteritis | Crohn's |