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Renal System O1
Renal blood flow and GFR- Hamra- 1/30-31/2013
| Question | Answer |
|---|---|
| Normal GFR | 180 L/day |
| Oncotic pressure in the glomerulus rises faster in high or low flow? | Low |
| As RBF increases, GFR | Increases |
| Filtration fraction is higher at high or low flows? | Low flows |
| Which factor dominates GFR changes in slight vasoconstriction? | Pgc |
| Which factor dominates GFR changes in severe vasoconstriction? | Renal plasma flow |
| Explain why the PTC's have a relatively high oncotic pressure | The fluid filtration out of the glomeruli leaves the proteins behind which increases the PCT oncotic pressure |
| Explain why the PTCs have a relatively low hydrostatic pressure | The high resistance in the efferent arteriole means that the hydrostatic pressure downstream is lower than normal |
| Autoregulation includes which two processes? | Myogenic response and Tubuloglomerular feeback |
| The myogenic response responds to a stretch of smooth muscle with | An increase in constriction of the arteriolar smooth muscle |
| Renal blood flow and GFR are help constant in which BP range | 80-180 mmHg |
| If the macula densa senses too much NaCl in the distal tubule, a signal is sent to | the afferent arteriole to constrict (via adenisine) |
| As blood pressure increases, afferent arteriolar resistance | Increases |
| A low dose of Dopamine causes | Vasodilation |